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In-hospital mortality risk prediction after percutaneous coronary interventions: Validating and updating the Toronto score in Brazil.
Lodi-Junqueira, Lucas; da Silva, José L P; Ferreira, Lorena R; Gonçalves, Humberto L; Athayde, Guilherme R S; Gomes, Thalles O; Borges, Júlio C; Nascimento, Bruno R; Lemos, Pedro A; Ribeiro, Antônio L P.
Afiliação
  • Lodi-Junqueira L; Department of Interventional Cardiology, Hospital Das Clínicas, Universidade Federal De Minas Gerais, Belo Horizonte, Brazil.
  • da Silva JL; Department of Statistics, Institute of Exact Sciences, Universidade Federal De Minas Gerais, Belo Horizonte, Brazil.
  • Ferreira LR; Department of Internal Medicine, School of Medicine, Universidade Federal De Minas Gerais, Belo Horizonte, Brazil.
  • Gonçalves HL; Department of Interventional Cardiology, Hospital Das Clínicas, Universidade Federal De Minas Gerais, Belo Horizonte, Brazil.
  • Athayde GR; Department of Interventional Cardiology, Hospital Das Clínicas, Universidade Federal De Minas Gerais, Belo Horizonte, Brazil.
  • Gomes TO; Department of Interventional Cardiology, Hospital Das Clínicas, Universidade Federal De Minas Gerais, Belo Horizonte, Brazil.
  • Borges JC; Department of Interventional Cardiology, Hospital Das Clínicas, Universidade Federal De Minas Gerais, Belo Horizonte, Brazil.
  • Nascimento BR; Department of Interventional Cardiology, Hospital Das Clínicas, Universidade Federal De Minas Gerais, Belo Horizonte, Brazil.
  • Lemos PA; Department of Internal Medicine, School of Medicine, Universidade Federal De Minas Gerais, Belo Horizonte, Brazil.
  • Ribeiro AL; Department of Interventional Cardiology, Heart Institute, University of São Paulo Medical School, São Paulo, Brazil.
Catheter Cardiovasc Interv ; 86(6): E239-46, 2015 Nov 15.
Article em En | MEDLINE | ID: mdl-25754488
OBJECTIVES: We aimed to assess the accuracy of the simple, contemporary and well-designed Toronto PCI mortality risk score in ICP-BR registry, the first Brazilian PCI multicenter registry with follow-up information. BACKGROUND: Estimating percutaneous coronary intervention (PCI) mortality risk by a clinical prediction model is imperative to help physicians, patients and family members make informed clinical decisions and optimize participation in the consent process, reducing anxiety and improving quality of care. At a healthcare system level, risk prediction scores are essential to measure and benchmark performance. METHODS: Between 2009 and 2013, a cohort of 4,806 patients from the ICP-BR registry, treated with PCI in eight tertiary referral medical centers, was included in the analysis. This population was compared to 10,694 patients of the derivation dataset from the Toronto study. To assess predictive performance, an update of the model was performed by three different methods, which were compared by discrimination, calculating the area under the receiver operating characteristic curve (AUC), and by calibration, assessed through Hosmer-Lemeshow (H-L) test and graphical analysis. RESULTS: Death occurred in 2.6% of patients in the ICP-BR registry and in 1.3% in the Toronto cohort. The median age was 64 and 63 years, 23.8 and 32.8% were female, 28.6 and 32.3% were diabetics, respectively. Through recalibration of intercept and slope (AUC = 0.8790; H-L P value = 0.3132), we achieved a well-calibrated and well-discriminative model. CONCLUSIONS: After updating to our dataset, we demonstrated that the Toronto PCI in-hospital mortality risk score performed well in Brazilian hospitals.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Sistema de Registros / Mortalidade Hospitalar / Intervenção Coronária Percutânea Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / America do sul / Brasil Idioma: En Revista: Catheter Cardiovasc Interv Assunto da revista: CARDIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Sistema de Registros / Mortalidade Hospitalar / Intervenção Coronária Percutânea Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / America do sul / Brasil Idioma: En Revista: Catheter Cardiovasc Interv Assunto da revista: CARDIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos