Prevalence of Hb S (HHB: c.20A > T) in a Honduran population of African descent.
Hemoglobin
; 39(2): 134-7, 2015.
Article
em En
| MEDLINE
| ID: mdl-25707678
Sickle cell disease is the most common hemoglobinopathy worldwide, particularly in Africa and among people of African descent. Serious clinical consequences characterize the homozygous condition. To determine the prevalence of Hb S (HBB: c.20A > T) and anemia in a community of people of African descent from Honduras, 202 individuals were analyzed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). The high prevalence found indicates that it is necessary to implement a program to prevent the consequences of this disease in vulnerable populations of Honduras.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemoglobina Falciforme
/
População Negra
/
Globinas beta
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Anemia Falciforme
/
Mutação
Tipo de estudo:
Diagnostic_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
/
Child
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Child, preschool
/
Female
/
Humans
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Infant
/
Male
/
Pregnancy
País/Região como assunto:
America central
/
Honduras
Idioma:
En
Revista:
Hemoglobin
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Honduras
País de publicação:
Reino Unido