Pivotal role of serum- and glucocorticoid-inducible kinase 1 in vascular inflammation and atherogenesis.

Borst, Oliver; Schaub, Malte; Walker, Britta; Schmid, Evi; Münzer, Patrick; Voelkl, Jakob; Alesutan, Ioana; Rodríguez, José M; Vogel, Sebastian; Schoenberger, Tanja; Metzger, Katja; Rath, Dominik; Umbach, Anja; Kuhl, Dietmar; Müller, Iris I; Seizer, Peter; Geisler, Tobias; Gawaz, Meinrad; Lang, Florian

Borst, Oliver; Schaub, Malte; Walker, Britta; Schmid, Evi; Münzer, Patrick; Voelkl, Jakob; Alesutan, Ioana; Rodríguez, José M; Vogel, Sebastian; Schoenberger, Tanja; Metzger, Katja; Rath, Dominik; Umbach, Anja; Kuhl, Dietmar; Müller, Iris I; Seizer, Peter; Geisler, Tobias; Gawaz, Meinrad; Lang, Florian.

Afiliação

Borst O; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Schaub M; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Walker B; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Schmid E; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Münzer P; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Voelkl J; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Alesutan I; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Rodríguez JM; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Vogel S; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Schoenberger T; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Metzger K; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Rath D; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Umbach A; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Kuhl D; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Müller II; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Seizer P; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Geisler T; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Gawaz M; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T
Lang F; From the Department of Cardiology and Cardiovascular Medicine (O.B., M.S., S.V., T.S., K.M., D.R., I.I.M., P.S., T.G., M.G.), Department of Physiology (O.B., B.W., E.S., P.M., J.V., I.A., A.U., F.L.), Department of Pediatric Surgery and Urology, University Children's Hospital (E.S.), University of T

Arterioscler Thromb Vasc Biol ; 35(3): 547-57, 2015 Mar.

Article em En | MEDLINE | ID: mdl-25614279

Assuntos

Doenças da Aorta/enzimologia; Aterosclerose/enzimologia; Doenças das Artérias Carótidas/enzimologia; Quimiotaxia; Proteínas Imediatamente Precoces/metabolismo; Inflamação/enzimologia; Proteínas Serina-Treonina Quinases/metabolismo; Transporte Ativo do Núcleo Celular; Animais; Aorta/enzimologia; Aorta/patologia; Doenças da Aorta/genética; Doenças da Aorta/patologia; Apolipoproteínas E/deficiência; Apolipoproteínas E/genética; Aterosclerose/genética; Aterosclerose/patologia; Artérias Carótidas/enzimologia; Artérias Carótidas/patologia; Doenças das Artérias Carótidas/genética; Doenças das Artérias Carótidas/patologia; Linhagem Celular; Modelos Animais de Doenças; Regulação Enzimológica da Expressão Gênica; Humanos; Quinase I-kappa B/metabolismo; Proteínas I-kappa B/metabolismo; Proteínas Imediatamente Precoces/deficiência; Proteínas Imediatamente Precoces/genética; Inflamação/genética; Inflamação/patologia; Macrófagos/enzimologia; Macrófagos/patologia; Masculino; Metaloproteinase 2 da Matriz/metabolismo; Metaloproteinase 9 da Matriz/genética; Metaloproteinase 9 da Matriz/metabolismo; Camundongos Endogâmicos C57BL; Camundongos Knockout; Mutação; Subunidade p50 de NF-kappa B/metabolismo; Peritonite/induzido quimicamente; Peritonite/enzimologia; Peritonite/genética; Placa Aterosclerótica; Proteínas Serina-Treonina Quinases/deficiência; Proteínas Serina-Treonina Quinases/genética; Transdução de Sinais; Tioglicolatos; Transcrição Gênica; Transfecção; Remodelação Vascular

Palavras-chave

atherosclerosis; inflammation; migration and invasion protein; serum-glucocorticoid regulated kinase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças da Aorta / Doenças das Artérias Carótidas / Quimiotaxia / Proteínas Serina-Treonina Quinases / Proteínas Imediatamente Precoces / Aterosclerose / Inflamação Tipo de estudo: Prognostic_studies Idioma: En Revista: Arterioscler Thromb Vasc Biol Assunto da revista: ANGIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de publicação: Estados Unidos

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