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[Squamous neoplasia of the ocular surface in patients with pterygium in Peru]. / Neoplasia escamosa de la superficie ocular en pacientes con pterigión en Perú
Furuya-Kanamori, Luis; Dulanto-Reinoso, Carlos M; Stone, Jennifer C; Marroquín, Lelia; Dulanto-Reinoso, Victor Ch; Roca, José A; Contreras, Francisco; Lee, Graham A.
Afiliação
  • Furuya-Kanamori L; The University of Queensland, Brisbane, Australia.
  • Dulanto-Reinoso CM; Instituto Nacional de Oftalmología, Lima, Perú
  • Stone JC; The University of Queensland, Brisbane, Australia.
  • Marroquín L; Instituto Nacional de Oftalmología, Lima, Perú
  • Dulanto-Reinoso VCh; Universidad de de Sao Paulo, Sao Paulo, Brasil.
  • Roca JA; Servicio de Oftalmología, Clínica Ricardo Palma, Lima, Perú
  • Contreras F; Universidad Peruana Cayetano Heredia, Lima, Perú
  • Lee GA; The University of Queensland, Brisbane, Australia.
Rev Peru Med Exp Salud Publica ; 31(4): 689-94, 2014.
Article em Es | MEDLINE | ID: mdl-25597719
OBJECTIVES: To estimate the frequency of unsuspected ocular surface squamous neoplasia (OSSN) in pterygium, the accuracy of clinical diagnosis, and associated demographic and clinical characteristics. MATERIALS AND METHODS: We reviewed histopathological reports of patients with a clinical diagnosis of pterygium and/or OSSN who were surgically treated between March 2009 and December 2012 at the National Eye Institute in Lima, Peru. The accuracy of the clinical diagnosis of OSSN was assessed by sensitivity, specificity, and likelihood ratios. Models of negative log-log regression were performed to identify demographic and clinical characteristics associated with increased odds of diagnosing OSSN. RESULTS: 3,021 histopathological reports were reviewed. The frequency of unsuspected OSSN in pterygium was 0.65%. Clinical diagnosis had a sensitivity of 85%, a specificity of 99%, a positive likelihood ratio of 111.89, and a negative likelihood ratio of 0.15. Associated characteristics were male gender (OR =1.15; 95% CI: 1.01 to 1.30), age group of 61-80 years (OR = 1.54, 95% CI: 1.28 to 1.85) ≥ 81 years (OR = 3.10; 95% CI: 2.09 to 4.58), presence of recurrent lesions (OR = 1.59; 95% CI: 1.03 to 2.46) and temporal location lesions (OR = 3.57; 95% CI: 2.63 to 4.85). These characteristics were associated with a greater likelihood of OSSN. CONCLUSIONS: A low frequency of unsuspected OSSN was found; however, it is recommended to routinely perform histopathology studies to avoid misdiagnosis of OSSN as pterygium.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pterígio / Carcinoma de Células Escamosas / Neoplasias Oculares Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Peru Idioma: Es Revista: Rev Peru Med Exp Salud Publica Assunto da revista: SAUDE PUBLICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália País de publicação: Peru
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pterígio / Carcinoma de Células Escamosas / Neoplasias Oculares Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Peru Idioma: Es Revista: Rev Peru Med Exp Salud Publica Assunto da revista: SAUDE PUBLICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Austrália País de publicação: Peru