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Inflammatory bowel disease in Hispanic communities: a concerted South American approach could identify the aetiology of Crohn's disease and ulcerative colitis.
Farrukh, Affifa; Mayberry, John Francis.
Afiliação
  • Farrukh A; Department of Digestive Diseases, University Hospitals of Leicester NHS Trust, Leicester, UK, United Kingdom.
  • Mayberry JF; Department of Digestive Diseases, University Hospitals of Leicester NHS Trust, Leicester, UK, United Kingdom.
Arq Gastroenterol ; 51(4): 271-5, 2014.
Article em En | MEDLINE | ID: mdl-25591153
Despite intensive research we remain ignorant of the cause of both Crohn's disease and ulcerative colitis. The dramatic rise in incidence, particularly of Crohn's disease, points towards environmental factors as playing a significant role. A major purpose of this review is to stimulate a co-ordinated international effort to establish an on-going data base in Central and South America in which new cases are registered and through which investigations into aetiology can be conducted. In both Brazil and Mexico there is evidence that the incidence of ulcerative colitis is increasing, as also is the case for Crohn's disease in Brazil. The pattern of disease is, therefore, directly comparable to that reported from Europe and the USA during the 1970s and 1980s, but much lower than contemporary data from Spain. Although the incidence is similar to that reported from Portugal, the studies from Almada and Braga were conducted a decade before that from Sao Paulo. The situation in Brazil compares dramatically with Uruguay and Argentina where the reported incidence of inflammatory bowel disease is significantly less. However, with growing industrialisation it is likely that there will be an explosion of inflammatory bowel disease in some areas of Central and South America over the next 20 years. The creation of a network of researchers across South and Central America is a real possibility and through a Concerted Action there is the possibility that major strides could be made towards understanding the cause of inflammatory bowel disease and so develop preventive strategies.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Doença de Crohn Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: America central / America do sul / Europa Idioma: En Revista: Arq Gastroenterol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Doença de Crohn Tipo de estudo: Prognostic_studies Limite: Humans País/Região como assunto: America central / America do sul / Europa Idioma: En Revista: Arq Gastroenterol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Brasil