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Acute eccentric resistance exercise decreases matrix metalloproteinase activity in obese elderly women.
Nascimento, Dahan da Cunha; Navalta, James Wilfred; Durigan, João Luiz Quagliotti; Marqueti, Rita de Cassia; Tibana, Ramires Alsamir; Luiz Franco, Octavio; de Almeida, Jesser Alves; Camarço, Nathalia Ferreira; Neto, Ivo Vieira de Sousa; Prestes, Jonato.
Afiliação
  • Nascimento Dda C; Graduate Program on Physical Education, Catholic University of Brasilia, Brasilia, Brazil.
  • Navalta JW; Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, NV, USA.
  • Durigan JL; University of Brasilia, Brasilia, Brazil.
  • Marqueti Rde C; University of Brasilia, Brasilia, Brazil.
  • Tibana RA; Graduate Program in Health Sciences and Technologies, University of Brasilia, Brasilia, Brazil.
  • Luiz Franco O; Graduate Program on Physical Education, Catholic University of Brasilia, Brasilia, Brazil.
  • de Almeida JA; Center for Proteomic and Biochemical Analyses, Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil.
  • Camarço NF; Center for Proteomic and Biochemical Analyses, Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil.
  • Neto IV; Graduate Program in Health Sciences and Technologies, University of Brasilia, Brasilia, Brazil.
  • Prestes J; Graduate Program on Physical Education, Catholic University of Brasilia, Brasilia, Brazil.
Clin Physiol Funct Imaging ; 36(2): 139-45, 2016 Mar.
Article em En | MEDLINE | ID: mdl-25523909
The association of ageing with obesity commits elderly women and has been correlated with multiple degenerative processes, which could be occasioned by an enhancing in levels of matrix metalloproteinase-2 and metalloproteinase-9 (MMPs) as well by an cytokine unbalance that included an enhancing on interleukin-6 (IL-6). Furthermore, other factors could be also related to degenerative process, as they could be reduced by eccentric resistance exercise (ERE), which seems particularly important to initiate resistance training in obese older adults. In this view, this study aims to determinate the effects of an acute ERE session on serum MMP-2, MMP-9 and IL-6 in elderly obese women. Ten elderly obese women participated in this study and completed a 10 repetitions maximum test (10 RM) utilizing leg extension exercise. Subjects then completed an acute ERE session consisting of seven sets of 10 repetitions at 110% of 10 RM with a rest of 3 min between sets. Blood samples were collected before, immediately after, 3, 24 and 48 h following the ERE session. Zymograms were utilized to measure the MMP-2 and MMP-9 enzymes from all individuals. Moreover, IL-6 concentration was also determinated. After ERE session, MMP-2 and MMP-9 decreased, remaining significantly below baseline values after 48 h (P<0·05). Although not statistically significant, there was a tendency for IL-6 to decrease 48 h after the ERE when compared with 3 h (P = 0·06). An acute ERE session decreases MMP-9, MMP-2 and IL-6 in elderly obese women, possibly indicating a transient protection against the low grade inflammation present in this specific population.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metaloproteinase 2 da Matriz / Metaloproteinase 9 da Matriz / Treinamento Resistido / Obesidade Tipo de estudo: Diagnostic_studies Limite: Aged / Female / Humans / Middle aged Idioma: En Revista: Clin Physiol Funct Imaging Assunto da revista: FISIOLOGIA / PATOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metaloproteinase 2 da Matriz / Metaloproteinase 9 da Matriz / Treinamento Resistido / Obesidade Tipo de estudo: Diagnostic_studies Limite: Aged / Female / Humans / Middle aged Idioma: En Revista: Clin Physiol Funct Imaging Assunto da revista: FISIOLOGIA / PATOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido