Absence of circadian rhythms of preterm premature rupture of membranes and preterm placental abruption.
Ann Epidemiol
; 24(12): 882-7, 2014 Dec.
Article
em En
| MEDLINE
| ID: mdl-25453346
PURPOSE: Data regarding circadian rhythm in the onset of spontaneous preterm premature rupture of membranes (PROM) and placental abruption (PA) cases are conflicting. We modeled the time of onset of preterm PROM and PA cases and examined if the circadian profiles varied based on the gestational age at delivery. METHODS: We used parametric and nonparametric methods, including trigonometric regression in the framework of generalized linear models, to test the presence of circadian rhythms in the time of onset of preterm PROM and PA cases among 395 women who delivered a singleton between 2009 and 2010 in Lima, Peru. RESULTS: We found a diurnal circadian pattern, with a morning peak at 07:32 AM (95% confidence interval, 05:46 AM09:18 AM) among moderate preterm PROM cases (P value < .001), and some evidence of a diurnal circadian periodicity among PA cases in term infants (P value = .067). However, we did not find evidence of circadian rhythms in the time of onset of extremely or very preterm PROM (P value = .259) and preterm PA (P value = .224). CONCLUSIONS: The circadian rhythms of the time of onset of preterm PROM and PA cases varied based on gestational weeks at delivery. Although circadian rhythms were presented among moderate preterm PROM and term PA cases, there was no evidence of circadian rhythms among preterm PA and very or extremely preterm PROM cases, underlying other mechanisms associated with the time of onset.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ruptura Prematura de Membranas Fetais
/
Ritmo Circadiano
/
Descolamento Prematuro da Placenta
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Newborn
/
Pregnancy
País/Região como assunto:
America do sul
/
Peru
Idioma:
En
Revista:
Ann Epidemiol
Assunto da revista:
EPIDEMIOLOGIA
Ano de publicação:
2014
Tipo de documento:
Article
País de publicação:
Estados Unidos