Combination topical therapy for conjunctival primary acquired melanosis with atypia and periocular lentigo maligna.
Cornea
; 34(1): 90-3, 2015 Jan.
Article
em En
| MEDLINE
| ID: mdl-25393090
PURPOSE: To report the case of a patient who initially presented with primary acquired melanosis (PAM) without atypia of the conjunctiva and later developed lentigo maligna of the eyelids and PAM with atypia of the conjunctiva. We illustrate the utility of combination topical therapy with adjunctive cryotherapy to treat extensive eyelid and conjunctival lesions. METHODS: Case report with a review of the current literature. RESULTS: Combination of imiquimod 5% cream (Aldara, 3M Pharmaceuticals) and cryotherapy for periorbital lentigo maligna with topical interferon-α2b for conjunctival PAM with atypia led to clinical resolution of pigmented lesions for 21 months. CONCLUSIONS: In our experience, combination topical therapy provides an effective alternative to surgery with superior cosmetic and functional outcomes.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Protocolos de Quimioterapia Combinada Antineoplásica
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Sarda Melanótica de Hutchinson
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Crioterapia
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Doenças da Túnica Conjuntiva
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Neoplasias Palpebrais
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Melanose
Limite:
Aged80
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Female
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Humans
Idioma:
En
Revista:
Cornea
Ano de publicação:
2015
Tipo de documento:
Article
País de publicação:
Estados Unidos