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Prevalence, correlates, and prognosis of peripheral artery disease in rural ecuador-rationale, protocol, and phase I results of a population-based survey: an atahualpa project-ancillary study.
Del Brutto, Oscar H; Sedler, Mark J; Mera, Robertino M; Castillo, Pablo R; Cusick, Elizabeth H; Gruen, Jadry A; Phelan, Kelsie J; Del Brutto, Victor J; Zambrano, Mauricio; Brown, David L.
Afiliação
  • Del Brutto OH; School of Medicine, Universidad Espíritu Santo-Ecuador, Guayaquil, Ecuador ; Air Center 3542, P.O. Box 522970, Miami, Fl 33152-2970, USA.
  • Sedler MJ; School of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USA.
  • Mera RM; Gastroenterology Department, Vanderbilt University, Nashville, TN, USA.
  • Castillo PR; Sleep Disorders Center, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
  • Cusick EH; School of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USA.
  • Gruen JA; School of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USA.
  • Phelan KJ; School of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USA.
  • Del Brutto VJ; Community Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas, Ecuador.
  • Zambrano M; Community Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas, Ecuador.
  • Brown DL; Cardiovascular Division, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8086, St. Louis, MO 63110, USA.
Int J Vasc Med ; 2014: 643589, 2014.
Article em En | MEDLINE | ID: mdl-25389500
Background. Little is known on the prevalence of peripheral artery disease (PAD) in developing countries. Study design. Population-based study in Atahualpa. In Phase I, the Edinburgh claudication questionnaire (ECQ) was used for detection of suspected symptomatic PAD; persons with a negative ECQ but a pulse pressure ≥65 mmHg were suspected of asymptomatic PAD. In Phase II, the ankle-brachial index will be used to test reliability of screening instruments and to determine PAD prevalence. In Phase III, participants will be followed up to estimate the relevance of PAD as a predictor of vascular outcomes. Results. During Phase I, 665 Atahualpa residents aged ≥40 years were enrolled (mean age: 59.5 ± 12.6 years, 58% women). A poor cardiovascular health status was noticed in 464 (70%) persons of which 27 (4%) had a stroke and 14 (2%) had ischemic heart disease. Forty-four subjects (7%) had suspected symptomatic PAD and 170 (26%) had suspected asymptomatic PAD. Individuals with suspected PAD were older, more often women, and had a worse cardiovascular profile than those with nonsuspected PAD. Conclusions. Prevalence of suspected PAD in this underserved population is high. Subsequent phases of this study will determine whether prompt detection of PAD is useful to reduce the incidence of catastrophic vascular diseases in the region.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference País/Região como assunto: America do sul / Ecuador Idioma: En Revista: Int J Vasc Med Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference País/Região como assunto: America do sul / Ecuador Idioma: En Revista: Int J Vasc Med Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos