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Review of experimental attempts of islet allotransplantation in rodents: parameters involved and viability of the procedure.
Iuamoto, Leandro Ryuchi; Meyer, Alberto; Chaib, Eleazar; D'Albuquerque, Luiz Augusto Carneiro.
Afiliação
  • Iuamoto LR; Leandro Ryuchi Iuamoto, Alberto Meyer, Eleazar Chaib, Luiz Augusto Carneiro D'Albuquerque, Department of Gastroenterology, Liver and Pancreas Transplantation Surgery Unit, University of Sao Paulo, Sao Paulo 05403-090, Brazil.
  • Meyer A; Leandro Ryuchi Iuamoto, Alberto Meyer, Eleazar Chaib, Luiz Augusto Carneiro D'Albuquerque, Department of Gastroenterology, Liver and Pancreas Transplantation Surgery Unit, University of Sao Paulo, Sao Paulo 05403-090, Brazil.
  • Chaib E; Leandro Ryuchi Iuamoto, Alberto Meyer, Eleazar Chaib, Luiz Augusto Carneiro D'Albuquerque, Department of Gastroenterology, Liver and Pancreas Transplantation Surgery Unit, University of Sao Paulo, Sao Paulo 05403-090, Brazil.
  • D'Albuquerque LA; Leandro Ryuchi Iuamoto, Alberto Meyer, Eleazar Chaib, Luiz Augusto Carneiro D'Albuquerque, Department of Gastroenterology, Liver and Pancreas Transplantation Surgery Unit, University of Sao Paulo, Sao Paulo 05403-090, Brazil.
World J Gastroenterol ; 20(37): 13512-20, 2014 Oct 07.
Article em En | MEDLINE | ID: mdl-25309081
The purpose of the present study was to organize the parameters involved in experimental allotransplantation in rodents to elaborate the most suitable model to supply the scarcity of islet donors. We used the PubMed database to systematically search for published articles containing the keywords "rodent islet transplantation" to review. We included studies that involved allotransplantation experiments with rodents' islets, and we reviewed the reference lists from the eligible publications that were retrieved. We excluded articles related to isotransplantation, autotransplantation and xenotransplantation, i.e., transplantation in other species. A total of 25 studies related to allotransplantation were selected for systematic review based on their relevance and updated data. Allotransplantation in rodents is promising and continues to develop. Survival rates of allografts have increased with the discovery of new immunosuppressive drugs and the use of different graft sites. These successes suggest that islet transplantation is a promising method to overcome the scarcity of islet donors and advance the treatment options for type 1 diabetes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante das Ilhotas Pancreáticas / Ilhotas Pancreáticas / Diabetes Mellitus Tipo 1 / Sobrevivência de Enxerto Tipo de estudo: Systematic_reviews Limite: Animals Idioma: En Revista: World J Gastroenterol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante das Ilhotas Pancreáticas / Ilhotas Pancreáticas / Diabetes Mellitus Tipo 1 / Sobrevivência de Enxerto Tipo de estudo: Systematic_reviews Limite: Animals Idioma: En Revista: World J Gastroenterol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos