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Expression of Galectins 1, 3 and 9 in normal oral epithelium, oral squamous papilloma, and oral squamous cell carcinoma.
Hossaka, Thais Ayako; Ribeiro, Daniel A; Focchi, Gustavo; André, Sabine; Fernandes, Mariana; Lopes Carapeto, Fernando Cintra; Silva, Marcelo Souza; Oshima, Celina T F.
Afiliação
  • Hossaka TA; Department of Pathology, Federal University of São Paulo, UNIFESP, SP, Brazil.
  • Ribeiro DA; Department of Pathology, Federal University of São Paulo, UNIFESP, SP, Brazil ; Department of Biosciences, Federal University of São Paulo, UNIFESP, SP, Brazil.
  • Focchi G; Department of Pathology, Federal University of São Paulo, UNIFESP, SP, Brazil.
  • André S; Institute of Physiological Chemistry, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich, Germany.
  • Fernandes M; Department of Pathology, Federal University of São Paulo, UNIFESP, SP, Brazil.
  • Lopes Carapeto FC; Department of Pathology, Federal University of São Paulo, UNIFESP, SP, Brazil.
  • Silva MS; Department of Pathology, Federal University of São Paulo, UNIFESP, SP, Brazil.
  • Oshima CT; Department of Pathology, Federal University of São Paulo, UNIFESP, SP, Brazil.
Dent Res J (Isfahan) ; 11(4): 508-12, 2014 Jul.
Article em En | MEDLINE | ID: mdl-25225566
BACKGROUND: The aim of this study was to characterize the immunohistochemical expression of galectin 1, 3, and 9 in normal oral epithelium, oral squamous papilloma, and oral squamous cell carcinoma. MATERIALS AND METHODS: Immunohistochemical staining for galectins 1, 3, and 9 was evaluated in 8 samples of normal oral squamous epithelium, 15 samples of oral squamous papilloma, and 41 samples of oral squamous cell carcinoma. Immunohistochemical data were assessed by Kruskal-Wallis non-parametric test followed by Dunn's test. For all analyzes, it was adopted the value of P <0.05 for statistical significance. RESULTS: Significant differences were found in galectin- 3 expression when comparing ordinary mucosa and oral squamous papilloma with the oral squamous cell carcinoma samples. CONCLUSION: These findings indicate that galectin-3 is closely involved in malignant transformation of oral mucosa cells.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Dent Res J (Isfahan) Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Irã
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Dent Res J (Isfahan) Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Irã