Effects of undernutrition on the ontogeny of muscarinic receptors and acetylcholinesterase activity in the rat motor cortex.
Braz J Med Biol Res
; 22(8): 959-61, 1989.
Article
em En
| MEDLINE
| ID: mdl-2517407
The effect of undernutrition on the ontogeny of muscarinic receptor density and acetylcholinesterase (AChE) activity was studied in the motor cerebral cortex homogenates of female Wistar rats aged 12-19 days, 2-3 months and 5-8 months. Experimental animals were fed a protein-calorie deficient diet. The binding assays, using (3H)-N-methylscopolamine as a ligand, indicated a significant increase in muscarinic receptor density in the motor cortex of 5-8-month old control rats (36%) compared to neonatal controls. No increase was observed for undernourished rats at any of the ages studied. No significant difference was observed in AChE activity at any age of either group studied.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acetilcolinesterase
/
Receptores Muscarínicos
/
Desnutrição Proteico-Calórica
/
Córtex Motor
Limite:
Animals
Idioma:
En
Revista:
Braz J Med Biol Res
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil