Studies on aldose reductase inhibitors from natural products. II. Active components of a Paraguayan crude drug "Para-parai mí," Phyllanthus niruri.
Chem Pharm Bull (Tokyo)
; 37(9): 2531-2, 1989 Sep.
Article
em En
| MEDLINE
| ID: mdl-2514047
Aldose reductase (AR) inhibitory activity-directed fractionation of the 70% ethanolic extract of Para-parai mí, Phyllanthus niruri, has led to the isolation of three active components, ellagic acid (1), brevifolin carboxylic acid (4) and ethyl brevifolin carboxylate (5). Among them, 1 showed the highest inhibitory activity, being about 6 times more potent than quercitrin, which is a known natural inhibitor of AR.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plantas Medicinais
/
Desidrogenase do Álcool de Açúcar
/
Aldeído Redutase
Limite:
Animals
País/Região como assunto:
America do sul
/
Paraguay
Idioma:
En
Revista:
Chem Pharm Bull (Tokyo)
Ano de publicação:
1989
Tipo de documento:
Article
País de publicação:
Japão