The epidemiology of HIV transmission among paid plasma donors, Mexico City, Mexico.
AIDS
; 3(10): 631-3, 1989 Oct.
Article
em En
| MEDLINE
| ID: mdl-2512956
ABSTRACT
PIP: This report provides the results of a study of plasma donor clients from records abstracted between June-October 1986. The purpose was to identify risk factors for HIV infection among donors at the National Center for Blood Transfusions. Screening for HIV among donors began in May 1986. 54 Seropositive donors were identified and located from 281 and 58 seronegative donors were randomly selected. 16 employees of the plasma collection center were locatable and also included in the study. The results were that seroprevalence increased between June-October from 6.3% to 9.2%. The total donations were 3201 of which 294 were seropositive. Of 281 seropositive clients, 62 (22%) had seroconversion (a prior seronegative donation). Seroconversions increased from 1.6% in July to 50% in October. On retesting of the 112 study participants, no change in status was found. The groups were similar and both groups had relatively low risk factors for (13% for HIV seropositive and 15.5% for HIV seronegative donors). The rate of seropositivity increased with the frequency of plasma donations from 19.6% for those donating 1-3 times/month to 88.9% for those donating 10 times/month. Of the 16 employees, 1 died who was HIV seropositive; 5 were directly involved in plasma collection and reported reuse of saline solution and intravenous tubing. The results lead the authors to suggest that HIV was transmitted in the collection process. Support for this suggestion comes from the number of seroconversions; the risk factors among the seropositive donors had no known risk factors. Although not statistically significant, male seropositive donors had greater contract with prostitutes in Mexico City, but prostitutes had shown in the past 2 years a seropositivity rate of 1%. More demonstrative evidence comes from the increased rate of seropositivity with frequency of donation, and the employee reports of reutilization of blood collection materials. Other studies have postulated plasma donor site risk. Regardless of the expense of intravenous equipment, it is suggested that the risk of HIV transmission precludes reuse of materials. At present, all blood is collected from volunteer donors with disposable equipment. Other countries need to assess the safety of blood donor centers, particularly with paid donors.
Palavras-chave
Acquired Immunodeficiency Syndrome--prevention and control; Americas; Behavior; Biology; Developing Countries; Diseases; Examinations And Diagnoses; Health; Hematologic Tests--standards; Hiv Infections--prevention and control; Hygiene; Laboratory Examinations And Diagnoses; Laboratory Procedures; Latin America; Management; Measurement; Medical Supervision; Mexico; North America; Organization And Administration; Prevalence; Public Health; Research Methodology; Research Report; Risk Factors; Screening; Supervision; Viral Diseases; Voluntarism
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bancos de Sangue
/
Doadores de Sangue
/
Soropositividade para HIV
/
Contenção de Riscos Biológicos
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Adult
/
Female
/
Humans
/
Male
País/Região como assunto:
Mexico
Idioma:
En
Revista:
AIDS
Assunto da revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
México
País de publicação:
Reino Unido