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Catheter-directed thrombolysis in the treatment of acute deep venous thrombosis: a meta-analysis.
Zheng, J J; Zhang, Z H; Shan, Z; Wang, W J; Li, X X; Wang, S M; Li, Y-X; Cheng, G-S.
Afiliação
  • Zheng JJ; Cardiac Surgery, The First Affiliated Hospital of Xi'an Jiaotong University School of Medicine, Xi'an, Shaan Xi, China JianJieZhengcn@163.com.
  • Zhang ZH; Department of Vascular Surgery, The First Affiliated Hospital of Zhongshan University, Guangzhou, Guangdong, China.
  • Shan Z; Department of Vascular Surgery, The First Affiliated Hospital of Zhongshan University, Guangzhou, Guangdong, China.
  • Wang WJ; Department of Vascular Surgery, The First Affiliated Hospital of Zhongshan University, Guangzhou, Guangdong, China.
  • Li XX; Department of Vascular Surgery, The First Affiliated Hospital of Zhongshan University, Guangzhou, Guangdong, China.
  • Wang SM; Department of Vascular Surgery, The First Affiliated Hospital of Zhongshan University, Guangzhou, Guangdong, China.
  • Li YX; Cardiac Surgery, The First Affiliated Hospital of Xi'an Jiaotong University School of Medicine, Xi'an, Shaan Xi, China.
  • Cheng GS; Second Department of Cardiology, The First Affiliated Hospital of Xi'an Jiaotong University School of Medicine, Xi'an, Shaan Xi, China.
Genet Mol Res ; 13(3): 5241-9, 2014 Jul 24.
Article em En | MEDLINE | ID: mdl-25078578
We performed a meta-analysis for systematic evaluation of the status quo of catheter thrombolysis for the treatment of acute lower limb deep vein thrombosis in China. We searched the China Biomedical bibliographic database (CBM), China National Knowledge Infrastructure (CNKI), Weipu full-text electronic journals, Wanfang full-text database, and Medline (1990 through June 2011) for clinical randomized controlled trials of catheter-directed thrombolysis and superficial venous thrombolysis to compare their efficacies for the treatment of acute deep vein thrombosis. The results were analyzed by using the Cochrane-recommended RevMan 4.2 software package, and the odds ratio (OR) was used as the combined measure of efficacy. The search retrieved 8 randomized controlled trials, and meta-analysis using the total rate of effective treatment as the clinical observation index found that the combined OR for the catheter thrombolysis group versus the superficial venous thrombolysis group was significant (P < 0.01; OR = 11.78; 95% confidence interval = 6.99-19.87). In conclusion, the meta-analysis indicated that catheter thrombolysis was more effective than superficial venous thrombolysis for the treatment of acute deep vein thrombosis in the lower limb in Chinese individuals. However, the included trials were only of medium quality, so more rational and scientific clinical trials are needed to validate this conclusion.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cateterismo Periférico / Trombose Venosa / Fibrinolíticos Tipo de estudo: Clinical_trials / Etiology_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: China País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cateterismo Periférico / Trombose Venosa / Fibrinolíticos Tipo de estudo: Clinical_trials / Etiology_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Genet Mol Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: China País de publicação: Brasil