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Artificial tears alone versus 0.45% ketorolac tromethamine with artificial tears for the treatment of acute viral conjunctivitis.
Lyra, Adriana Falcão Veloso; Bastos, Lílian Correia; Lima, Raquel Coelho de Souza; Maranhão, Lúcio de Vieira Leite; Arantes, Tiago Eugênio.
Afiliação
  • Lyra AF; Fundação Altino Ventura, Recife, PE, Brazil.
  • Bastos LC; Fundação Altino Ventura, Recife, PE, Brazil.
  • Lima RC; Fundação Altino Ventura, Recife, PE, Brazil.
  • Maranhão Lde V; Fundação Altino Ventura, Recife, PE, Brazil.
  • Arantes TE; Fundação Altino Ventura, Recife, PE, Brazil.
Arq Bras Oftalmol ; 77(2): 99-102, 2014 Apr.
Article em En | MEDLINE | ID: mdl-25076474
PURPOSE: To evaluate the effects of preservative-free 0.45% ketorolac tromethamine and artificial tears (carboxymethylcellulose) compared with those of preservative-free artificial tears alone on the symptoms and signs of acute viral conjunctivitis. METHODS: This was a randomized, double-masked clinical trial that included 50 patients who were diagnosed with acute viral conjunctivitis and distributed into two groups (Group 0: artificial tears and Group 1: 0.45% ketorolac tromethamine + carboxymethylcellulose). The patients were instructed to use the medication 4 times daily. Signs (conjunctival hyperemia, chemosis, follicles, and secretion) and symptoms (general ocular discomfort, itching, foreign body sensation, tearing, redness, and swelling of the eyelids) were scored at baseline and on the third and seventh days of treatment using a standardized questionnaire and slitlamp anterior segment examination. RESULTS: Both groups showed an improvement in the signs and symptoms of conjunctivitis in their follow-up visits. There was no significant difference in symptom and sign scores between Group 0 and Group 1 in the study visits (p>0.05). The frequency of side effects during treatment was similar between groups (p>0.05). CONCLUSIONS: Our findings indicate that 0.45% ketorolac tromethamine was not superior to the use of artificial tears in relieving the signs and symptoms of viral conjunctivitis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Soluções Oftálmicas / Anti-Inflamatórios não Esteroides / Conjuntivite Viral / Cetorolaco de Trometamina / Lubrificantes Oftálmicos Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Arq Bras Oftalmol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Soluções Oftálmicas / Anti-Inflamatórios não Esteroides / Conjuntivite Viral / Cetorolaco de Trometamina / Lubrificantes Oftálmicos Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male Idioma: En Revista: Arq Bras Oftalmol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil