Sorption of norfloxacin in soils: analytical method, kinetics and Freundlich isotherms.
Chemosphere
; 119: 310-317, 2015 Jan.
Article
em En
| MEDLINE
| ID: mdl-25036946
Fluoroquinolones are potent antibacterial agents that are active against a wide range of pathogenic organisms and are widely used in veterinary medicine. Fluoroquinolones and their metabolites may reach the soil through animal excreta or manure and may contaminate water and soils. The degree of sorption of these antimicrobials to soils varies widely, as does the mobility of these drugs. In the present study, sorption of norfloxacin in four soils of the state of São Paulo was investigated with batch equilibrium experiments. A strong matrix effect on the chromatographic determination of norfloxacin was verified. Sorption kinetics were best fit by a pseudo second-order model (r>0.99), and sorption/desorption isotherms were well fit by the Freundlich model in log form (r>0.97). Norfloxacin showed high affinity for soil particles, with KF sorption values ranging from 643 to 2410 µg(1-1/n)(cm(3))(1/n)g(-1) and KF desorption values ranging from 686 to 2468 µg(1-1/n)(cm(3))(1/n)g(-1). The high desorption KF values indicate that norfloxacin is highly immobile in the evaluated soils.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poluentes do Solo
/
Norfloxacino
/
Antibacterianos
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
Chemosphere
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Reino Unido