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Ethanol-induced effects on sting extension response and punishment learning in the western honey bee (Apis mellifera).
Giannoni-Guzmán, Manuel A; Giray, Tugrul; Agosto-Rivera, Jose Luis; Stevison, Blake K; Freeman, Brett; Ricci, Paige; Brown, Erika A; Abramson, Charles I.
Afiliação
  • Giannoni-Guzmán MA; Department of Biology, University of Puerto Rico Rio Piedras, San Juan, Puerto Rico.
  • Giray T; Department of Biology, University of Puerto Rico Rio Piedras, San Juan, Puerto Rico.
  • Agosto-Rivera JL; Department of Biology, University of Puerto Rico Rio Piedras, San Juan, Puerto Rico.
  • Stevison BK; Laboratory of Behavioral Biology and Comparative Psychology, Oklahoma State University, Stillwater, Oklahoma, United States of America.
  • Freeman B; Laboratory of Behavioral Biology and Comparative Psychology, Oklahoma State University, Stillwater, Oklahoma, United States of America.
  • Ricci P; Laboratory of Behavioral Biology and Comparative Psychology, Oklahoma State University, Stillwater, Oklahoma, United States of America.
  • Brown EA; Laboratory of Behavioral Biology and Comparative Psychology, Oklahoma State University, Stillwater, Oklahoma, United States of America.
  • Abramson CI; Laboratory of Behavioral Biology and Comparative Psychology, Oklahoma State University, Stillwater, Oklahoma, United States of America.
PLoS One ; 9(7): e100894, 2014.
Article em En | MEDLINE | ID: mdl-24988309
Acute ethanol administration is associated with sedation and analgesia as well as behavioral disinhibition and memory loss but the mechanisms underlying these effects remain to be elucidated. During the past decade, insects have emerged as important model systems to understand the neural and genetic bases of alcohol effects. However, novel assays to assess ethanol's effects on complex behaviors in social or isolated contexts are necessary. Here we used the honey bee as an especially relevant model system since bees are typically exposed to ethanol in nature when collecting standing nectar crop of flowers, and there is recent evidence for independent biological significance of this exposure for social behavior. Bee's inhibitory control of the sting extension response (SER) and a conditioned-place aversion assay were used to study ethanol effects on analgesia, behavioral disinhibition, and associative learning. Our findings indicate that although ethanol, in a dose-dependent manner, increases SER thresholds (analgesic effects), it disrupts the ability of honey bees to inhibit SER and to associate aversive stimuli with their environment. These results suggest that ethanol's effects on analgesia, behavioral disinhibition and associative learning are common across vertebrates and invertebrates. These results add to the use of honey bees as an ethanol model to understand ethanol's effects on complex, socially relevant behaviors.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Abelhas / Comportamento Animal / Depressores do Sistema Nervoso Central / Etanol / Aprendizagem Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Porto Rico País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Abelhas / Comportamento Animal / Depressores do Sistema Nervoso Central / Etanol / Aprendizagem Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Porto Rico País de publicação: Estados Unidos