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Depression increases in patients with Parkinson?s disease according to the increasing severity of the cognitive impairment.
Chagas, Marcos Hortes N; Moriyama, Tais S; Felício, André C; Sosa, Ana Luisa; Bressan, Rodrigo A; Ferri, Cleusa P.
Afiliação
  • Chagas MH; Departamento de Neurociências e Ciências do Comportamento, Universidade de São Paulo, Ribeirao Preto, SP, Brazil.
  • Moriyama TS; Departamento de Psiquiatria, Laboratório Interdisciplinar de Neurociências Clínicas, Universidade Federal de São Paulo, Sao Paulo, SP, Brazil.
  • Felício AC; Instituto Israelita de Ensino e Pesquisa, Hospital Israelita Albert Einstein, Sao Paulo, SP, Brazil.
  • Sosa AL; National Institute of Neurology and Neurosurgery of México, Mexico City, México.
  • Bressan RA; Departamento de Psiquiatria, Laboratório Interdisciplinar de Neurociências Clínicas, Universidade Federal de São Paulo, Sao Paulo, SP, Brazil.
  • Ferri CP; Departamento de Psicobiologia, Universidade Federal de São Paulo, Sao Paulo, SP, Brazil.
Arq Neuropsiquiatr ; 72(6): 426-9, 2014 Jun.
Article em En | MEDLINE | ID: mdl-24964108
OBJECTIVE: To test the hypothesis that severity of cognitive impairment modifies the association between depression and Parkinson's disease (PD). METHOD: One-phase population-based door-to-door surveys. This is a secondary analysis of 1,451 people aged 65 years and older with cognitive impairment living in defined catchment areas. Depression was estimated according to ICD-10, self-reported PD, disability according to WHODAS-II and cognitive status according to the CSI-D. RESULTS: The mean age of the sample was 79.3 years old and most (69%) were women. Of the total sample, 16.1% had depression and it was significantly higher among participants with PD. There was an increase on the ORs of the association between depression and PD with decreased scores in the cognitive test (Adjusted OR from 0.98 to 8.04). CONCLUSION: The association between depression and PD increases with the severity of the cognitive impairment.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Transtornos Cognitivos / Transtorno Depressivo Tipo de estudo: Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Aged80 / Female / Humans / Male Idioma: En Revista: Arq Neuropsiquiatr Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Transtornos Cognitivos / Transtorno Depressivo Tipo de estudo: Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Aged80 / Female / Humans / Male Idioma: En Revista: Arq Neuropsiquiatr Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha