Your browser doesn't support javascript.
loading
Autologous Fat Grafting for Treatment of Breast Implant Capsular Contracture: A Study in Pigs.
Roça, Guilherme Berto; Graf, Ruth; da Silva Freitas, Renato; Salles, Guataçara; Francisco, Julio Cesar; Noronha, Lucia; Maluf, Ivan.
Afiliação
  • Roça GB; Dr Roça is a plastic surgeon in private practice in Curitiba, Paraná, Brazil contato@guilhermeroca.com.br.
  • Graf R; Dr Graf is Professor, Dr Freitas is Professor and Head of Unit, and Mr Maluf is a resident in the Plastic Surgery Unit, Federal University of Paraná, Brazil.
  • da Silva Freitas R; Dr Graf is Professor, Dr Freitas is Professor and Head of Unit, and Mr Maluf is a resident in the Plastic Surgery Unit, Federal University of Paraná, Brazil.
  • Salles G; Drs Salles, Francisco, and Noronha are Professors at Pontifical Catholic University of Paraná, Brazil.
  • Francisco JC; Drs Salles, Francisco, and Noronha are Professors at Pontifical Catholic University of Paraná, Brazil.
  • Noronha L; Drs Salles, Francisco, and Noronha are Professors at Pontifical Catholic University of Paraná, Brazil.
  • Maluf I; Dr Graf is Professor, Dr Freitas is Professor and Head of Unit, and Mr Maluf is a resident in the Plastic Surgery Unit, Federal University of Paraná, Brazil.
Aesthet Surg J ; 34(5): 769-75, 2014 Jul.
Article em En | MEDLINE | ID: mdl-24963064
BACKGROUND: Capsular contracture (CC) is a common complication after breast augmentation. Autologous fat grafting may be effective for restoring tissue vascularization and function. OBJECTIVE: The authors evaluated the efficacy of autologous fat grafting in a porcine model as a treatment for CC after breast augmentation. METHODS: This prospective study was performed in 20 female 30-day-old pigs. Each animal was implanted with three 30-cc textured silicone implants (stage 1 of the experiment). Group A served as the untreated control group. To induce CC, 2 mL of autologous fibrin glue was applied to the pericapsular space in group B and C animals at implantation. Three months after implantation (stage 2), the CCs of all groups were assessed by Baker classification and applanation tonometry (AT). Liposuction was performed in group B to harvest fat for these animals. Three months after group B underwent fat grafting, all 3 groups were reevaluated. Reassessments included Baker classification, AT, histologic analysis, and tensiometry (stage 3). RESULTS: The deposition of mature and immature collagen was similar for the 3 groups. The amount of fat remaining around the implanted capsules did not differ significantly between the groups. At stage 3, group B exhibited significantly larger tonometry areas than did group C. The CCs in groups B and C were significantly thicker than those of group A, but the difference between groups B and C was not significant. Capsule rupture forces did not differ significantly between groups A and B but were significantly higher in group C compared with the other groups. CONCLUSIONS: Results in this animal model indicate that pericapsular lipoinjection may be a promising treatment for CC in humans.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Implante Mamário / Contratura Capsular em Implantes Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Aesthet Surg J Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tecido Adiposo / Implante Mamário / Contratura Capsular em Implantes Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Aesthet Surg J Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido