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[Metabolic changes associated with obesity in adults]. / Alteraciones metabólicas asociadas a la obesidad en adultos.
Rincón, E; Ryder, E; Valbuena, H; García de Zambrano, N; Campos, G; Morales, L M; Semprún de Fereira, M; Wilhelm, I.
Afiliação
  • Rincón E; Escuela de Medicina, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela.
Invest Clin ; 30(4): 229-49, 1989.
Article em Es | MEDLINE | ID: mdl-2488710
In order to find if the metabolic disorders more frequently found in our obese population were similar to the ones reported in the literature for other countries, a study was conducted in a group of 34 obese subjects (10 men and 24 women) whose only apparent alteration was a body mass index above 30 (mean value: 36.8 +/- 4.6) to obtain the relation between anthropometric measurements (Quetelet index, skinfold measures and waist/hip ratio) and plasma levels of nine biochemical parameters (including lipids, lipoproteins and glucose and insulin levels after an oral glucose load). The results revealed a tendency to the android distribution of fat in the female population, a significantly elevated triglyceride and total lipids levels and a decreased in HDL-cholesterol in both sexes. Hypercholesterolemia was present mainly in the male population. The most frequent dyslipidemia was Type IV (23%) followed by type IIb (15%). Practically none of the subjects had abnormal glycemic values after the glucose load, however the insulin levels were highly elevated in 80% of the patients, resulting in a great insulin/glucose ratios. Correlation analysis showed no association of the BMI with any biochemical parameter; only the insulin area was positively associated with anthropometric measures (mainly waist/hip ratio) and with the most altered biochemical parameter, the triglycerides. Variance analysis showed that only low HDL-cholesterol values were significantly different in patients presenting high blood pressure and familiar history of diabetes.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Obesidade Tipo de estudo: Risk_factors_studies Limite: Adolescent / Adult / Child / Female / Humans / Male / Middle aged Idioma: Es Revista: Invest Clin Ano de publicação: 1989 Tipo de documento: Article País de afiliação: Venezuela País de publicação: Venezuela
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Obesidade Tipo de estudo: Risk_factors_studies Limite: Adolescent / Adult / Child / Female / Humans / Male / Middle aged Idioma: Es Revista: Invest Clin Ano de publicação: 1989 Tipo de documento: Article País de afiliação: Venezuela País de publicação: Venezuela