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Migraine is frequent in children and adolescents with neurofibromatosis type 1.
Pinho, Ricardo Silva; Fusão, Eduardo Ferracioli; Paschoal, Joelma Karina Sagica Fernandes; Caran, Eliana Maria Monteiro; Minett, Thaís Soares Cianciarullo; Vilanova, Luiz Celso Pereira; Masruha, Marcelo Rodrigues.
Afiliação
  • Pinho RS; Department of Neurology and Neurosurgery, Federal University of São Paulo, São Paulo, Brazil.
  • Fusão EF; Department of Neurology and Neurosurgery, Federal University of São Paulo, São Paulo, Brazil.
  • Paschoal JKSF; Department of Neurology and Neurosurgery, Federal University of São Paulo, São Paulo, Brazil.
  • Caran EMM; Department of Pediatrics/Pediatric Oncology Institute and Support Group for Children and Adolescents with Cancer, Federal University of São Paulo, São Paulo, Brazil.
  • Minett TSC; Department of Public Health and Primary Care, Cambridge University, Cambridge, UK.
  • Vilanova LCP; Department of Neurology and Neurosurgery, Federal University of São Paulo, São Paulo, Brazil.
  • Masruha MR; Department of Neurology and Neurosurgery, Federal University of São Paulo, São Paulo, Brazil.
Pediatr Int ; 56(6): 865-867, 2014 Dec.
Article em En | MEDLINE | ID: mdl-24832054
BACKGROUND: Despite the high prevalence of headache in patients with neurofibromatosis type 1 (NF1), little data exist regarding the classification and characterization of headaches experienced by these patients. This paper describes a study of headache in patients with NF1 compared with healthy controls. METHODS: In this transversal study, participants (aged 4-19 years) were classified into two groups: NF1 patients or control subjects. The diagnosis of NF1 was performed according to the diagnostic criteria of the National Institutes of Health Consensus Conference, and the headache diagnosis was performed according to the diagnostic criteria of the International Classification of Headache Disorders, Second Edition. All participants underwent physical and neurologic evaluation and completed a detailed headache questionnaire. RESULTS: The comparison of 50 patients with NF1 and 50 age-matched controls revealed that the complaint of headache was significantly more frequent in the NF1 group than in the control group (CG) (62% vs 14%, χ(2)(1) = 22.4; P < 0.001). Migraine was significantly more frequent in patients with NF1 than in the CG (54% vs 14%, χ(2)(1) = 17.82; P < 0.001). No differences were found between the two groups regarding the use of simple analgesics (NF1: 14% vs CG: 5%, χ(2)(1) = 1.18; P = 0.276). CONCLUSIONS: Children and adolescents with NF1 are prone to migraines. Complaints of headache are very frequent in this population.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibromatose 1 / Transtornos de Enxaqueca Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Pediatr Int Assunto da revista: PEDIATRIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Austrália
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibromatose 1 / Transtornos de Enxaqueca Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Pediatr Int Assunto da revista: PEDIATRIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Austrália