Anesthetic management of a pediatric patient with leigh syndrome.
Braz J Anesthesiol
; 63(2): 220-2, 2013.
Article
em En
| MEDLINE
| ID: mdl-24565130
BACKGROUND AND OBJECTIVES: Leigh syndrome (LS) is a rare disease caused by abnormalities of mitochondrial energy generation. The central nervous system is most frequently affected, with psychomotor underdevelopment, seizures, nystagmus, ophthalmoparesis, optic atrophy, ataxia, dystonia, or respiratory failure. Surgical and anesthetic procedures stimulate the tracheal irritability, and could exacerbate risks of aspiration, wheezing, breathing difficulties, gasping, hypoventilation, and apnea. CASE REPORT: We present the anesthetic management for a six-year-old boy with severe form of LS, involving repair of a femur fracture. Propofol and remifentanil were infused for general anesthesia. The patient was closely monitored during anesthesia and in the intensive care unit in the early postoperative period. CONCLUSIONS: Close intraoperative monitoring of patients, including invasive arterial blood pressure monitoring and frequently measuring the levels of blood gases, glucose, and lactate, made this procedure run smoothly. Intensive care and breathing support for the patient with LS, under sedation with an analgesic combination during the early postoperative period, minimized the stress response due to pain after surgery.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Piperidinas
/
Doença de Leigh
/
Propofol
/
Anestésicos Intravenosos
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Fraturas do Fêmur
/
Anestesia Geral
Limite:
Child
/
Humans
/
Male
Idioma:
En
Revista:
Braz J Anesthesiol
Ano de publicação:
2013
Tipo de documento:
Article
País de publicação:
Brasil