In vitro effects of Musa x paradisiaca extracts on four developmental stages of Haemonchus contortus.
Res Vet Sci
; 96(1): 127-32, 2014 Feb.
Article
em En
| MEDLINE
| ID: mdl-24382490
This study was carried out to evaluate the in vitro effect of Musa x paradisiaca stem and leaf against the parasitic nematode of small ruminants Haemonchus contortus. Three extracts (aqueous, methanolic and/or dichloromethane) of Musa x paradisiaca stem and leaf were tested in vitro on four developmental stages of H. contortus using egg hatch assay (EHA), larval development assay (LDA), L3 migration inhibition assay (LMI) and adult worm motility assay (AWM). The highly significant (P<0.0001) ability to stop larval development (inhibition >67% for each extract) and the negative effect of the dichloromethane extract of leaf on adult worm motility (43% of inhibition of motility after 24h of incubation) compared to the negative controls, suggest anthelmintic properties of Musa x paradisiaca stem and leaf against H. contortus. The active principles responsible for the activity could be secondary metabolites such as terpenoid and flavonoid compounds present in the leaf and stem of the plant.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Extratos Vegetais
/
Musa
/
Haemonchus
/
Fitoterapia
/
Anti-Helmínticos
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
País/Região como assunto:
Caribe
/
Guadalupe
Idioma:
En
Revista:
Res Vet Sci
Ano de publicação:
2014
Tipo de documento:
Article
País de publicação:
Reino Unido