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Primary cutaneous anaplastic large-cell lymphoma--case report.
Oliveira, Luciana Silveira Rabello de; Nobrega, Madeleyne Palhano; Monteiro, Maira Gomes; Almeida, Wagner Leite de.
Afiliação
  • Oliveira LS; Federal University of Campina Grande, Campina GrandePB, Brazil.
  • Nobrega MP; Center for Endocrinology and Metabolism, Campina GrandePB, Brazil.
  • Monteiro MG; Federal University of Campina Grande, University Hospital Alcides Carneiro, Campina GrandePB, Brazil.
  • Almeida WL; Campinense Unit of Diagnosis, Campina GrandePB, Brazil.
An Bras Dermatol ; 88(6 Suppl 1): 132-5, 2013.
Article em En | MEDLINE | ID: mdl-24346900
Primary cutaneous anaplastic large-cell lymphoma is part of the spectrum of CD30+ lymphoproliferative cutaneous processes, characterized by single or multifocal nodules that ulcerate, are autoregressive and recurrent. Extracutaneous dissemination may occur, especially to regional lymph nodes. Histology shows a diffuse, non-epidermotropic infiltrate , anaplastic large lymphoid cells of immunohistochemistry CD30+, CD4+, EMA-/+, ALK-, CD15- and TIA1-/+. Prognosis is good and does not depend on lymphatic invasion. Radiotherapy, removal of the lesion and/or low-dose methotrexate are the treatments of choice. The present study reports the case of a 57-year-old-woman presenting Primary cutaneous anaplastic large-cell lymphoma with multifocal lesions. The patient evolved with pulmonary involvement 7 years later. She showed a good response to the treatment with low-dose methotrexate prescribed weekly.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Linfoma Anaplásico Cutâneo Primário de Células Grandes Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Middle aged Idioma: En Revista: An Bras Dermatol Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Linfoma Anaplásico Cutâneo Primário de Células Grandes Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Middle aged Idioma: En Revista: An Bras Dermatol Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha