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Tuberculosis deaths in a tertiary hospital in Goiânia, Brazil: a descriptive study.
Tavares, Camila; Lins, Tatiana Bacelar Acioli; Junqueira-Kipnis, Ana Paula; de Araújo-Filho, João Alves.
Afiliação
  • Tavares C; Tropical Pathology and Public Health Institute, Federal University of Goias; Tropical Diseases Hospital, Socrates Guanaes Institute, Goiania, GO, Brazil.
  • Lins TB; Tropical Pathology and Public Health Institute, Federal University of Goias; Tropical Diseases Hospital, Socrates Guanaes Institute, Goiania, GO, Brazil.
  • Junqueira-Kipnis AP; Tropical Pathology and Public Health Institute, Federal University of Goias; Tropical Diseases Hospital, Socrates Guanaes Institute, Goiania, GO, Brazil.
  • de Araújo-Filho JA; Tropical Pathology and Public Health Institute, Federal University of Goias; Tropical Diseases Hospital, Socrates Guanaes Institute, Goiania, GO, Brazil.
Infez Med ; 21(4): 279-86, 2013 Dec.
Article em En | MEDLINE | ID: mdl-24335458
Tuberculosis (TB) remains a serious global public health problem, being the main cause of death in patients with AIDS, and the third cause of death by infectious diseases throughout the world. This is somewhat surprising because TB is a disease that, if treated properly, displays high rates of healing. It is therefore important to characterise these patients to identify target populations for specific measures seeking to reduce TB deaths. We performed a retrospective descriptive study to analyse the cases of TB deaths in a State public hospital, a point of reference for treatment of infectious diseases, located in the Central-West region of Brazil, in the period from January 1st, 2008 to December 31st, 2009. There were 283 diagnosed and reported cases of TB between 2008 and 2009, and 39 recorded deaths occurred, resulting in a lethality index of 14%. The mean age of TB patients was 42 years, and the median age 37 years. Pulmonary TB was the most common form of TB (51.3% of the patients). Of the 39 TB patients who died, 56.4% (n = 22) were co-infected with HIV. The main immediate causes of death were acute respiratory failure (n = 12) and sepsis (n = 8). Anaemia and hypoalbuminaemia were prevalent in this group, and 27 patients required mechanical ventilation. This study found that hospitalized patients who died had the following characteristics: bilateral pulmonary disease, low levels of haemoglobin and haematocrit, albumin, and those co-infected with HIV that were admitted to the ICU required MV. Prospective studies aiming to analyse the risk factors for death from TB are needed to better understand this process.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Infez Med Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Brasil País de publicação: Itália
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Infez Med Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Brasil País de publicação: Itália