[Angioedema and paradoxical bronchoconstriction secondary to ipratropium bromide/salbutamol administered by metered dose inhaler in patients with soy allergy]. / Angioedema y broncoconstricción paradójica secundarios a bromuro de ipratropio/salbutamol administrados por inhalador de dosis medida en pacientes alérgicos a la soya.
Rev Alerg Mex
; 58(4): 219-23, 2011.
Article
em Es
| MEDLINE
| ID: mdl-24007833
BACKGROUND: There are some reports on the association between the use of ipratropium bromide/salbutamol and paradoxical bronchoconstriction and urticaria in patients with soy allergy. METHODS: We describe four patients who displayed angioedema and paradoxical bronchoconstriction secondary to ipratropium bromide/salbutamol administered by metereddose-inhaler (MDI). In all of them soy allergy was demonstrated. RESULTS: Four patients, two children and two adults, exhibited paradoxical bronchoconstriction and angioedema secondary to ipratropium bromide/salbutamol administered by MDI. In all of them, soy allergy was substantiated by skin prick test and IgG/IgE RAST. The symptoms quickly disappeared with antihistaminics and nebulized salbutamol. CONCLUSIONS: In the cases where paradoxical bronchoconstriction and angioedema associated with the use of ipratropium bromide/salbutamol in MDI an immediate hypersentivity reaction to soy was confirmed, which is used as an additive in the MDI, through allergen-specific IgE determination and skin tests.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Broncodilatadores
/
Broncoconstrição
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
Es
Revista:
Rev Alerg Mex
Ano de publicação:
2011
Tipo de documento:
Article
País de publicação:
México