Targeting the microbiota in the management of gastrointestinal and liver disease.
Rev Gastroenterol Peru
; 33(2): 139-44, 2013.
Article
em En
| MEDLINE
| ID: mdl-23838941
Thanks to rapid advances in technology the details of the human microbiome and its functions in health and disease are being progressively revealed. Though many reports have linked various disease states with an altered microbiome and while some associations between the microbiome and disease states are well established, many of these studies are largely descriptive and the changes reported in the microbiome have yet to be shown to be causative. A number of strategies are available to modify the microbiota; some such as the use of antibiotics for specific indications, are well established, others such as the use of probiotics and prebiotics in a variety of disease states are supported by more limited data. Fecal transplantation has emerged as an exciting, albeit rather drastic, intervention for intestinal and, perhaps, other disorders. Other approaches, such as the isolation, purification and formulation of small molecules with specific biological actions, derived from the microbiota look very promising.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Microbiota
/
Gastroenteropatias
/
Hepatopatias
Limite:
Humans
Idioma:
En
Revista:
Rev Gastroenterol Peru
Assunto da revista:
GASTROENTEROLOGIA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Estados Unidos
País de publicação:
Peru