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Emergence of Pseudomonas aeruginosa with KPC-type carbapenemase in a teaching hospital: an 8-year study.
Ramírez, Dolores García; Nicola, Federico; Zarate, Soledad; Relloso, Silvia; Smayevsky, Jorgelina; Arduino, Sonia.
Afiliação
  • Ramírez DG; Laboratory of Bacteriology, Mycology and Parasitology, Center of Medical Education and Clinical Research 'Norberto Quirno' (CEMIC), Buenos Aires, Argentina.
  • Nicola F; Laboratory of Bacteriology, Mycology and Parasitology, Center of Medical Education and Clinical Research 'Norberto Quirno' (CEMIC), Buenos Aires, Argentina.
  • Zarate S; Laboratory of Bacteriology, Mycology and Parasitology, Center of Medical Education and Clinical Research 'Norberto Quirno' (CEMIC), Buenos Aires, Argentina.
  • Relloso S; Laboratory of Bacteriology, Mycology and Parasitology, Center of Medical Education and Clinical Research 'Norberto Quirno' (CEMIC), Buenos Aires, Argentina.
  • Smayevsky J; Laboratory of Bacteriology, Mycology and Parasitology, Center of Medical Education and Clinical Research 'Norberto Quirno' (CEMIC), Buenos Aires, Argentina.
  • Arduino S; Laboratory of Bacteriology, Mycology and Parasitology, Center of Medical Education and Clinical Research 'Norberto Quirno' (CEMIC), Buenos Aires, Argentina.
J Med Microbiol ; 62(Pt 10): 1565-1570, 2013 Oct.
Article em En | MEDLINE | ID: mdl-23831767
An outbreak of Klebsiella pneumoniae carbapenamase (KPC)-producing K. pneumoniae occurred at our institution. Multiresistant Pseudomonas aeruginosa could have acquired this transmissible resistance mechanism, going unnoticed because its phenotypic detection in this species is difficult. We compared P. aeruginosa isolates obtained before and after the KPC-producing K. pneumoniae outbreak. No bla(KPC) genes were detected in the isolates obtained before the outbreak, whereas 33/76 (43%) of the isolates obtained after the outbreak harboured the bla(KPC) gene. P. aeruginosa may thus become a reservoir of this transmissible resistance mechanism. It is very important to understand the epidemiology of these multiresistant isolates, in order to achieve early implementation of adequate control measures to contain and reduce their dissemination in the hospital environment.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Infecções por Pseudomonas / Proteínas de Bactérias / Beta-Lactamases / Resistência beta-Lactâmica Limite: Humans País/Região como assunto: America do sul / Argentina Idioma: En Revista: J Med Microbiol Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Argentina País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Infecções por Pseudomonas / Proteínas de Bactérias / Beta-Lactamases / Resistência beta-Lactâmica Limite: Humans País/Região como assunto: America do sul / Argentina Idioma: En Revista: J Med Microbiol Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Argentina País de publicação: Reino Unido