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Impact of machines on plan quality: volumetric modulated arc therapy and intensity modulated radiation therapy.
Clemente, S; Cozzolino, M; Oliviero, C; Fiorentino, A; Chiumento, C; Fusco, V.
Afiliação
  • Clemente S; Department of Radiation Oncology, IRCCS CROB, Via Padre Pio n.1, 85028, Rionero in Vulture, PZ, Italy, clemente_stefania@libero.it.
Clin Transl Oncol ; 16(2): 141-6, 2014 Feb.
Article em En | MEDLINE | ID: mdl-23645162
PURPOSE: To evaluate the impact of different machines on plan quality using both intensity modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) techniques. MATERIALS AND METHODS: Eight patients with squamous cell carcinoma of the oropharynx were selected at random. Plans were computed for IMRT and VMAT Smart Arc, using Pinnacle TPS for an Elekta (IMRT-E, VMAT-E) and Varian linac (IMRT-V, VMAT-V). A three-dose level prescription was used to deliver 70, 63 and 58.1 Gy to regions of macroscopic, microscopic high- and low-risk disease, respectively. All doses were given in 35 fractions. Comparisons were performed on dose-volume histogram data, monitor units (MU), and delivery time. RESULTS: VMAT-E plans resulted slightly MU efficient (-24 % p < 0.05) compared to VMAT-V while IMRT-V shortened delivery time (-19 % p < 0.05) compared to IMRT-E. All the delivery techniques resulted in equivalent target coverage in terms of D(98) % and D(2) %. For VMAT technique, a significant improvement of 7 % in homogeneity index (HI) for PTV58.1 was observed for Varian machine. A slight improvement in OARs sparing was observed with Elekta machine both for IMRT and VMAT techniques. CONCLUSION: Similar plan quality was observed for Elekta and Varian linacs, significant differences were observed in delivery efficiency, as MU number and delivery times, in favor of Elekta and Varian, respectively.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aceleradores de Partículas / Planejamento da Radioterapia Assistida por Computador / Radioterapia de Intensidade Modulada Tipo de estudo: Clinical_trials / Etiology_studies Limite: Humans Idioma: En Revista: Clin Transl Oncol Ano de publicação: 2014 Tipo de documento: Article País de publicação: Itália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aceleradores de Partículas / Planejamento da Radioterapia Assistida por Computador / Radioterapia de Intensidade Modulada Tipo de estudo: Clinical_trials / Etiology_studies Limite: Humans Idioma: En Revista: Clin Transl Oncol Ano de publicação: 2014 Tipo de documento: Article País de publicação: Itália