Elderly hypertensives show decreased cognitive performance compared with elderly normotensives.
Arq Bras Cardiol
; 100(5): 444-51, 2013 May.
Article
em En, Pt
| MEDLINE
| ID: mdl-23579624
BACKGROUND: Essential hypertension has been associated with decreased cognitive performance; however, the literature is conflicting. OBJECTIVE: This study aims at comparing cognitive performance between elderly normotensives ("N"; n = 17; age 68 ± 1; blood pressure = 133 ± 3/74 ±2 mmHg) and hypertensives ("H"; n = 28; age 69 ± 1, blood pressure = 148 ± 4/80 ± 1mmHg) with at least 5 years of education. METHODS: The comprehensive neuropsychological assessment was comprised of the Cambridge Cognition-Revised (CAMCOG-R), the Trail Making Test A and B (TMT A and B) and the Rey Auditory Verbal Learning Test (RAVLT). RESULTS: Elderly hypertensives presented lower CAMCOG-R global scores (N = 87.6 ± 1.8; H = 78.6 ± 1.4; p = 0.002). The hypertensive's performance was slower in the TMT A and B (TMT A: N = 39 ± 3s; H = 57 ± 3s; p = 0.001; TMT B: N = 93 ± 7s; H = 124 ± 7s; p = 0.006), which was also reflected in smaller percentiles achieved by hypertensives in these tests. Hypertensive subjects exhibited a significantly lower RAVLT summation score (N = 51.8 ± 1.7; H = 40.7 ± 1.5; p < 0.0001). Even when adjusted for age, sex, education and depression symptoms, hypertension was an independent predictor of cognitive performance as measured by CAMCOG-R global score, TMT A and RAVLT summation score. CONCLUSION: Cognitive performance is lower in elderly hypertensives as compared with elderly normotensives.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pressão Sanguínea
/
Cognição
/
Hipertensão
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Limite:
Aged
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Female
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Humans
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Male
Idioma:
En
/
Pt
Revista:
Arq Bras Cardiol
Ano de publicação:
2013
Tipo de documento:
Article
País de publicação:
Brasil