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Coadjuvant treatment with surgery and pirfenidone in severe facial trauma due to dog bite.
Cantú-Cantú, María Zulema; Lyra-González, Iván; Armendáriz-Borunda, Juan.
Afiliação
  • Cantú-Cantú MZ; Hospital Pediátrico Tacubaya, Mexico City, Mexico.
J Craniofac Surg ; 24(2): 675-8, 2013 Mar.
Article em En | MEDLINE | ID: mdl-23524776
BACKGROUND: This case report assesses the effectiveness of surgery plus pirfenidone (PFD) as a concomitant therapy in the management of facial trauma after severe dog bite. METHODS: A 16-month-old female patient who suffered a severe attack by a big-sized dog (Rottweiler) in the midface area was managed with surgery/PFD combination and followed up for 20 months to evaluate the efficacy to control, prevent, and improve injury sequels. RESULTS: Surgery/PFD combination offered a good complementary therapy downregulating inflammatory activity, improving blood supply, and activating cytokine modulation and collagen synthesis/biosynthesis (scar control). No side effects were reported in this case report. CONCLUSIONS: Surgery/PFD management for severe facial dog bites represents a safe and effective therapeutic option to protect and improve a patient's quality of life, minimizing long-time sequels.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridonas / Mordeduras e Picadas / Anti-Inflamatórios não Esteroides / Traumatismos Faciais Aspecto: Patient_preference Limite: Animals / Female / Humans Idioma: En Revista: J Craniofac Surg Assunto da revista: ODONTOLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridonas / Mordeduras e Picadas / Anti-Inflamatórios não Esteroides / Traumatismos Faciais Aspecto: Patient_preference Limite: Animals / Female / Humans Idioma: En Revista: J Craniofac Surg Assunto da revista: ODONTOLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos