Primary antiphospholipid syndrome and panhypopituitarism: a unique presentation.

da Silva, Bárbara Santos Pires; Bonin, Camila; Bueno, Cristina Bellotti Formiga; Glezer, Andrea; Bronstein, Marcello D; Carvalho, Jozélio Freire

da Silva, Bárbara Santos Pires; Bonin, Camila; Bueno, Cristina Bellotti Formiga; Glezer, Andrea; Bronstein, Marcello D; Carvalho, Jozélio Freire.

Afiliação

da Silva BS; Biomedicine, Universidade Cidade de São Paulo, São Paulo, SP, Brazil.

Acta Reumatol Port ; 37(3): 272-5, 2012.

Article em En | MEDLINE | ID: mdl-23348118

RESUMO

Lymphocytic hypophysitis (LH) has been described previously in systemic lupus erythematosus (1.3%), Sjögren's syndrome (0.8%). Lymphocytic hypophysitis (LH) is rarely associated with rheumatic diseases, although three cases of pituitary disease associated with antiphospholipid syndrome (APS) have been described. Here, we report a possible association between APS and LH for the first time. A 34-yr-old woman with primary APS presented with polyuria, polydipsia, hypernatremia and impaired vision. Her hormone profile was compatible with panhypopituitarism, and sellar magnetic resonance imaging (MRI) depicted a normal pituitary gland with a thickened and displaced stalk and infundibulum portion. Hormone replacement was started, and the patient experienced a good clinical evolution.

Assuntos

Síndrome Antifosfolipídica/complicações; Hipopituitarismo/complicações; Adulto; Feminino; Humanos

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome Antifosfolipídica / Hipopituitarismo Limite: Adult / Female / Humans Idioma: En Revista: Acta Reumatol Port Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Brasil País de publicação: Portugal

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