[Hyperinsulinemic hypoglycemia of the infancy: analysis of clinical data from a Brazilian sample]. / Hipoglicemia hiperinsulinêmica da infância: Análise de dados clínicos de uma amostra brasileira.
Arq Bras Endocrinol Metabol
; 56(9): 666-71, 2012 Dec.
Article
em Pt
| MEDLINE
| ID: mdl-23329191
OBJECTIVE: To review the presentation of hyperinsulinemic hypoglycemia of the infancy (HHI), its treatment and histology in Brazilian pediatric endocrinology sections. MATERIALS AND METHOD: The protocol analyzed data of birth, laboratory results, treatment, surgery, and pancreas histology. RESULTS: Twenty-five cases of HHI from six centers were analyzed: 15 male, 3/25 born by vaginal delivery. The average age at diagnosis was 10.3 days. Glucose and insulin levels in the critical sample showed an average of 24.7 mg/dL and 26.3 UI/dL. Intravenous infusion of the glucose was greater than 10 mg/kg/min in all cases (M:19,1). Diazoxide was used in 15/25 of the cases, octreotide in 10, glucocorticoid in 8, growth hormone in 3, nifedipine in 2 and glucagon in 1. Ten of the cases underwent pancreatectomy and histology results showed the diffuse form of disease. CONCLUSION: This is the first critic review of a Brazilian sample with congenital HHI.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hiperinsulinismo Congênito
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Guideline
Limite:
Female
/
Humans
/
Infant
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Male
/
Newborn
País/Região como assunto:
America do sul
/
Brasil
Idioma:
Pt
Revista:
Arq Bras Endocrinol Metabol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil