[HPV detection in the mouth and cervix of patients with histological diagnosis suggestive of genital infection]. / Detección de VPH en boca y cérvix de pacientes con diagnóstico citológico sugestivo de infección genital.
An Sist Sanit Navar
; 35(3): 445-54, 2012.
Article
em Es
| MEDLINE
| ID: mdl-23296225
This work evaluated HPV infection in the oral cavity (using oroscopy and exfoliative oral cytology) and its relation to genital infection in women with cytological diagnosis suggestive of HPV infection. The sample consisted of 60 patients who underwent oroscopy, cytology and viral determination in mouth and cervix by PCR using generic primers MY09/MY11 and MPCR. HPV DNA was detected in oral and genital mucosa in 48.33% and 73.3% of patients, respectively, yielding a concordance of 44.2% (k=0.44, moderate agreement). The most common viral types were low risk, especially type 6, found in 86.2% of oral samples and 65.9% of cervical specimens, alone or in combination with other types of low (11) or high oncogenic risk (16, 18, 33), with a concordance of 10.45% (k = 0.1, insignificant agreement). However, in relation to type 6, there was a concordance of 75.86% (k=0.7, high agreement). The cytology of the oral cavity had a sensitivity of 3.5% and a specificity of 93.6%. For oroscopy, sensitivity was 27.6% and specificity was 74.2%. The results indicate that HPV infection in the oral cavity of patients with genital infection could be frequent. The low concordance between HPV types suggests that HPV infection in the mouth and cervix has a different biological behavior.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Papillomaviridae
/
Colo do Útero
/
Infecções por Papillomavirus
/
Doenças dos Genitais Femininos
/
Boca
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
Es
Revista:
An Sist Sanit Navar
Assunto da revista:
SAUDE PUBLICA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Venezuela
País de publicação:
Espanha