[Diastolic dysfunction in patients with human inmunodeficiency virus. Tissue Doppler study]. / Disfuncion diastolica en pacientes infectados con el virus de inmunodeficiencia humana. Estudio con Doppler tisular.
Rev Fac Cien Med Univ Nac Cordoba
; 69(2): 77-82, 2012.
Article
em Es
| MEDLINE
| ID: mdl-23286536
UNLABELLED: The heart has rarely been studied in patients infected with HIV. Diastolic dysfunction is the most frequently observed alteration , which could be due to direct viral action on the myocardium or due to autoimmune mechanism or concomitant infections by cardiotropic virus. The Doppler tissue is a more effective tool than the trans-mitral one to evaluate the diastolic function since is not influenced by preload, afterload or heart rate. OBJECTIVES: To study the prevalence of the left ventricular diastolic dysfunction (DDVI) in the HIV (+) group of patients, without symptoms or diagnosis of heart-disease and to analyze their relationship with the CD4 levels and the viral charge. MATERIAL AND METHODS: We prospectively studied 50 HIV(+) patients with no symptoms of cardiac involvement who underwent an echocardiogram using Doppler tissue compared with 50 healthy persons matched sex and age as control group. RESULTS: The infection of HIV was associated with DDVI and with CD4 Lymphocytes levels (p<0,05). The association between DDVI and viral load was not found. CONCLUSIONS: There is an association between the HIV infection and the presence of DDVI in asymptomatic patients. The long term monitoring studies should be considered in HIV (+) patients with silent diastolic dysfunction to evaluate their possible progression to the systolic dysfunction.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Disfunção Ventricular Esquerda
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Es
Revista:
Rev Fac Cien Med Univ Nac Cordoba
Ano de publicação:
2012
Tipo de documento:
Article
País de publicação:
Argentina