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Depressed eruption rate of the rat maxillary incisor in a drug-induced uncompensated hemolytic state model.
Giglio, M J; Sanz, A M; Bozzini, C E.
Afiliação
  • Giglio MJ; Department of Physiology, University of Buenos Aires, Faculty of Dentistry, Argentina.
J Dent Res ; 69(3): 906-8, 1990 Mar.
Article em En | MEDLINE | ID: mdl-2324356
Female rats weighing about 180 g were separated into two groups. One group (A) received phenylhydrazine (PHZ) every other day during three weeks (for induction of an uncompensated hemolytic state), while the control group (C) received saline. The evidence for the establishment of the uncompensated hemolytic state was obtained by hematocrit value, reticulocyte count, and red-cell-volume-59Fe uptake. Body-weight gain (which is a measure of overall body growth rate), body-length gain (which is a measure of longitudinal skeletal growth rate), food intake, and maxillary incisor eruption rate (ER) were significantly depressed in rats of group A during the PHZ-injection period, in relation to rats of group C. These results indicate that anemia and/or associated factors depress ER, along with body growth and skeletal growth.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Erupção Dentária / Anemia Hemolítica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Dent Res Ano de publicação: 1990 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Erupção Dentária / Anemia Hemolítica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Dent Res Ano de publicação: 1990 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos