[Variations of the hepatic SUV in relation to the body mass index in whole body PET-CT studies]. / Variaciones del SUV hepático con relación al índice de masa corporal en estudios PET/TC de cuerpo entero.
Rev Esp Med Nucl Imagen Mol
; 32(1): 26-32, 2013 Jan.
Article
em Es
| MEDLINE
| ID: mdl-23177341
OBJECTIVE: To evaluate SUV changes in the liver in relation to body mass index (BMI) of patients who undergo whole body PET-CT scans. MATERIAL AND METHODS: A retrospective study was performed. The variables studied were injected dose of (18F)FDG (mCi), age (years), blood glucose level (mg/dL), height (cm) and weight (kg). BMI was calculated and the SUV mean value was expressed according to gender and BMI. A linear regression analysis was applied to identify the independent variables that best predict the SUV value. RESULTS: Six hundred and three patients were studied (305 women, 298 men; mean age: 54.9±15.2 years old). Mean SUV measurement was significantly higher in males than females and increased significantly both in male and female patients who were overweight and even more in obese patients. The independent variables that best predicted the SUV value were gender, age, and BMI. In those patients having similar characteristics related to the analyzed variables, the SUV value increased by 0.002 for each increase in one year, and by 0.066 per unit increase in the BMI value. CONCLUSIONS: Hepatic uptake of (18F)FDG increases according to the patient's BMI. The independent variables that best predict the hepatic SUV value are age and sex of patients. Our findings show that the practice of using the physiological hepatic metabolic activity level as a reference regarding questionable deposits elsewhere in the abdomen and pelvis is not useful, at least in male patients with overweightness and obesity.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tomografia Computadorizada por Raios X
/
Índice de Massa Corporal
/
Compostos Radiofarmacêuticos
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Fluordesoxiglucose F18
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Tomografia por Emissão de Pósitrons
/
Imagem Corporal Total
/
Imagem Multimodal
/
Fígado
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Es
Revista:
Rev Esp Med Nucl Imagen Mol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
Espanha