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Analgesic and adjuvant anesthetic effect of submucosal tramadol after mandibular third molar surgery.
Ceccheti, Marcelo Minharro; Negrato, Giovana Vigário; Peres, Maria Paula Siqueira de Melo; Deboni, Maria Cristina Zindel; Naclério-Homem, Maria da Graça.
Afiliação
  • Ceccheti MM; Oral and Maxillofacial Surgery Department, General Clinics Hospital School of Medicine, University of Sao Paulo, São Paulo, Brazil.
  • Negrato GV; Oral and Maxillofacial Surgery Department, General Clinics Hospital School of Medicine, University of Sao Paulo, São Paulo, Brazil.
  • Peres MP; Dentistry Division, General Clinics Hospital, School of Medicine, University of Sao Paulo, São Paulo, Brazil.
  • Deboni MC; Oral and Maxillofacial Surgery Department, School of Dentistry, University of Sao Paulo, São Paulo, Brazil. Electronic address: mczdebon@usp.br.
  • Naclério-Homem Mda G; Oral and Maxillofacial Surgery Department, School of Dentistry, University of Sao Paulo, São Paulo, Brazil.
Oral Surg Oral Med Oral Pathol Oral Radiol ; 117(3): e249-54, 2014 Mar.
Article em En | MEDLINE | ID: mdl-22981094
OBJECTIVE: The aim of this study was to assess analgesic and adjuvant anesthetic effects of submucosal tramadol after third molar extraction. STUDY DESIGN: In this double-blind, split-mouth, placebo-controlled, single-dose, crossover investigation, 52 patients underwent mandibular third molar extraction under local anesthesia. Surgical side was randomly assigned to submucosal 2 mL 100 mg tramadol injection (group T) or normal saline solution (group P) immediately after surgery. Anesthetic blockade duration, time of intake and amount of analgesic rescue drug, and postoperative pain intensity were recorded immediately after anesthesia cessation and 4, 8, 24, 48, and 72 hours after surgery. Data were submitted to analysis of variance and Wilcoxon tests. RESULTS: Anesthetic blockade duration between groups was similar. Group T took significantly less rescue drug after 72 hours (P = .008). Time elapsed before first intake of rescue drug was longer (P = .006), and pain intensity was significantly lower (P = .001) in group T. CONCLUSIONS: Submucosal tramadol injection after oral surgery improved postoperative analgesia, but did not extend anesthetic action duration.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extração Dentária / Tramadol / Analgésicos Opioides / Adjuvantes Anestésicos / Dente Serotino Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extração Dentária / Tramadol / Analgésicos Opioides / Adjuvantes Anestésicos / Dente Serotino Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies Limite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: Oral Surg Oral Med Oral Pathol Oral Radiol Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos