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Periungual capillaroscopy in psoriasis.
Ribeiro, Camila Ferrari; Siqueira, Elisa Beatriz Dalledone; Holler, Ana Paula; Fabrício, Lincoln; Skare, Thelma Larocca.
Afiliação
  • Ribeiro CF; Department of Dermatology, Evangelical University Hospital of Curitiba, Evangelical College of Paraná, PR, Brazil.
An Bras Dermatol ; 87(4): 550-3, 2012.
Article em En | MEDLINE | ID: mdl-22892767
BACKGROUND: Nailfold capillaroscopy is a useful technique for evaluating changes in microcirculation. OBJECTIVE: To investigate changes at nailfold capillaroscopy in psoriatic patients compared with controls. METHODS: Nailfold capillaroscopy was performed in 46 psoriatic patients and 50 controls to assess microscopic morphological changes, capillary density and the presence of areas with devascularization. RESULTS: Patients with psoriasis had lower capillary density (p=0.0005), increased avascular areas (p=0.0035) and an increased number of morphologically abnormal capillaries (coiled, p<0.0001) compared to controls. No association was found between capillary density and the duration of the disease (p = 0.92) or the extent of skin involvement, as measured by the psoriasis area and severity index (PASI) score (p = 0.59). The presence of avascular areas was more common in psoriatic individuals whose nails were affected by the condition (p = 0.047). CONCLUSION: Patients with psoriasis have decreased capillary density and a greater presence of morphologically abnormal capillaries when compared to controls.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Angioscopia Microscópica / Microcirculação / Unhas Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: An Bras Dermatol Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Psoríase / Angioscopia Microscópica / Microcirculação / Unhas Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: An Bras Dermatol Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Brasil País de publicação: Espanha