[Hepatic lesions in acute cardiovascular failure in necropsy specimens]. / Valoración del daño hepático en el fallo agudo cardiocirculatorio en material de necropsias.
Acta Gastroenterol Latinoam
; 20(2): 81-8, 1990.
Article
em Es
| MEDLINE
| ID: mdl-2275312
To evaluate quali-quantitatively ischemic liver injury due to acute cardiocirculatory failure (ischemic hepatitis), and its real clinical signification, 200 out of 1165 autopsy records with ACF clinical diagnosis were selected; 33/200 (16.5%) shown centrilobular necrosis without inflammatory component, accompanied or not by midzonal compromise. Grade IV centrilobular necrosis (50-100% involved lobules) was present in 96.9%, with 15.5% associated midzonal pattern, and 21.2% of confluent type; 2 additional cases with isolated midzonal necrosis (5.7%) were seen. Only six patients (3.0% of ACF patients, and 18.2% of those with histological injury) shown overt clinical liver disease, one of them with a fulminant hepatitis picture (0.5% of ACF, and 3.0% of patients with ischemic necrosis). Bilirubin levels were 3.4-10.2 mg%, and aminotransferases rose up to 540 times over their seric superior normal limits. Centrilobular necrosis involved 100% of lobules in all cases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Parada Cardíaca
/
Isquemia
/
Fígado
/
Hepatopatias
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Es
Revista:
Acta Gastroenterol Latinoam
Ano de publicação:
1990
Tipo de documento:
Article
País de publicação:
Argentina