[Short-term antibiotic prophylaxis versus long-term antibiotic prophylaxis in major clean-contaminated maxillofacial surgery]. / Profilaxis antimicrobiana de corta duración versus profilaxis antimicrobiana de larga duración en cirugía maxilofacial mayor limpia-contaminada: Un estudio de cohorte.
Rev Chilena Infectol
; 29(1): 14-8, 2012 Feb.
Article
em Es
| MEDLINE
| ID: mdl-22552505
INTRODUCTION: There is no consensus on the most appropriate duration of antimicrobial prophylaxis (single or multiple dose) in clean-contaminated maxillofacial surgery. OBJECTIVE: To determine whether short-term antimicrobial prophylaxis is effective compared to long-term antimicrobial prophylaxis in preventing surgical site infection in clean-contaminated maxillofacial surgery. PATIENTS AND METHODS: The cohort study included 527 patients. We compared the incidence of surgical site infection in two groups. One group received short-term antibiotic prophylaxis (single dose) and the other group, long-term antimicrobial prophylaxis (multiple dose). RESULTS: The single dose group showed 5.7% of postoperative infections and the multiple-dose group, 5.9%, with an odds ratio of 0.96 (95% CI 0.44 to 2.10) p = 0.9214. CONCLUSION: No significant differences were found between the infection incidences in the single dose antibiotic prophylaxis group compared with the use of multiple doses.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecção da Ferida Cirúrgica
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Antibioticoprofilaxia
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Procedimentos Cirúrgicos Bucais
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Antibacterianos
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
Idioma:
Es
Revista:
Rev Chilena Infectol
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Chile
País de publicação:
Chile