Your browser doesn't support javascript.
loading
Oculomotor assessments of executive function in preterm children.
Loe, Irene M; Luna, Beatriz; Bledsoe, Ian O; Yeom, Kristen W; Fritz, Barbara L; Feldman, Heidi M.
Afiliação
  • Loe IM; Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA, USA.
J Pediatr ; 161(3): 427-433.e1, 2012 Sep.
Article em En | MEDLINE | ID: mdl-22480696
OBJECTIVE: To use objective, nonverbal oculomotor tasks to assess executive function and infer the neural basis of impairments in preterm children. STUDY DESIGN: Cross-sectional study of preterm children age 9-16 years (n = 69; mean gestational age 29 weeks) and full-term controls (n = 43). Tasks assessed sensorimotor function (reflexive prosaccades); resistance to peripheral distracters (fixation); response inhibition, response preparation, and execution of a voluntary saccade (antisaccades); and spatial working memory (memory-guided saccades). Group differences were analyzed using ANOVA. We used linear regression to analyze the contributions of age, sex, gestational age, and white matter category to task performance. RESULTS: Preterm children did not differ from controls on basic sensorimotor function, response inhibition, and working memory. Compared with controls, preterm children showed greater susceptibility to peripheral distracters (P = .008) and were slower to initiate an inhibitory response (P = .003). Regression models showed contributions of age and white matter category to task performance. CONCLUSIONS: Preterm children show intact basic sensorimotor function and demonstrate difficulties in processes underlying executive control, including increased distractibility and prolonged response preparation. These limitations may reflect specific neural abnormalities in fronto-subcortical executive control of behavior.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Recém-Nascido Prematuro / Movimentos Oculares / Função Executiva Tipo de estudo: Clinical_trials / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male / Newborn Idioma: En Revista: J Pediatr Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Recém-Nascido Prematuro / Movimentos Oculares / Função Executiva Tipo de estudo: Clinical_trials / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male / Newborn Idioma: En Revista: J Pediatr Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos