Measurement of blood flow in arteriovenous malformations before and after embolization using arterial spin labeling.
Interv Neuroradiol
; 18(1): 42-8, 2012 Mar.
Article
em En
| MEDLINE
| ID: mdl-22440600
The assessment of shunt reduction after an embolization of an arteriovenous malformation (AVM) or fistula (AVF) from conventional angiography is often difficult and may be subjective. Here we present a completely non-invasive method using magnetic resonance imaging (MRI) to measure shunt reduction. Using pulsed arterial spin labeling (PASL), we determined the relative amount of signal attributed to the shunt over 1.75 s and 6 different slices covering the lesion. This amount of signal from the shunt was related to the total signal from all slices and measured before and after embolization. The method showed a fair agreement between the PASL results and the judgement from conventional angiography. In the case of a total or subtotal shunt occlusion, PASL showed a shunt reduction between 69% and 92%, whereas in minimal shunt reduction as judged by conventional angiography, the ASL result was -6% (indicating slightly increased flow) to 35% in a partially occluded vein of Galen aneurysm. The PASL method proved to be fairly reproducible (up to 2% deviation between three measurements without interventions). On conclusion, PASL is able to reliably measure the amount of shunt reduction achieved by embolization of AVMs and AVFs.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Marcadores de Spin
/
Malformações Arteriovenosas Intracranianas
/
Circulação Cerebrovascular
/
Angiografia por Ressonância Magnética
/
Embolização Terapêutica
Tipo de estudo:
Observational_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Interv Neuroradiol
Assunto da revista:
NEUROLOGIA
/
RADIOLOGIA
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
República Dominicana
País de publicação:
Estados Unidos