Gait kinematic analysis evaluates hindlimb revascularization.
Proc West Pharmacol Soc
; 54: 21-3, 2011.
Article
em En
| MEDLINE
| ID: mdl-22423574
Peripheral arterial occlusive disease is described as vascular disorders associated with ischemia and may be the result of an obstructive vascular process or a lost revascularization response. We have shown that gait locomotion analysis by video filming represents an integrative model for the evaluation of mechanisms involved in the process of ischemia-induced revascularization. However, analysis by this method can be subjective and perception errors may be occurring. We present the optimization of a quantifiable, noninvasive, reproducible method that analyzes ankle kinematics in rats using a two-dimensional digital video system. Gait dynamics were filmed in hindlimb ischemic rats with a high speed digital video camera. Images were collected and analyzed at 125 frames per second. An algorithm using interactive data language (IDL) was devised to assess different parameters. In ischemic rats, stride time and knee joint angle remained altered 10 days post-surgery compared with sham animals. Gait kinematics were outlined in a highly reliable way by this computational analysis and corroborated the notion of hindlimb movement recovery associated with the revascularization process.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neovascularização Fisiológica
/
Marcha
/
Membro Posterior
Limite:
Animals
Idioma:
En
Revista:
Proc West Pharmacol Soc
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
México
País de publicação:
Estados Unidos