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[Ocular wavefront aberrations in patients with facial dystonia treated with botulinum toxin]. / Aberrações ópticas de alta ordem em pacientes com distonias faciais tratados com toxina botulínica.
Yabiku, Mariann Midori; Sartori, Juliana de Filippi; Sarraff, Eduardo Pantaleão; Osaki, Tammy Hentona; Hossaka, Sidarta Keizo; Pereira, Carolina Isolane; Freitas, Wilson de; Osaki, Midori Hentona; Cariello, Angelino Julio.
Afiliação
  • Yabiku MM; Departamento de Oftalmologia, Universidade Federal de São Paulo - UNIFESP - São Paulo (SP), Brazil.
Arq Bras Oftalmol ; 74(6): 414-6, 2011.
Article em Pt | MEDLINE | ID: mdl-22331113
PURPOSE: To analyze the ocular wavefront aberrations in patients with facial dystonia treated with botulinum toxin A. METHODS: Patients with benign essential blepharospasm and hemifacial spasm in activity underwent slit lamp examination and bilateral wavefront analysis under pharmacologic mydriasis using Alcon LADARvision wavefront aberrometry system. After that, all patients were treated with botulinum toxin A injections performed by the same ophthalmologist. After one month, the wavefront analysis was performed in the same way and by the same examiner. The main outcome measure was the change in ocular wavefront aberrations. Paired T-test was used to compare pre and post-injection numeric wavefront values. RESULTS: From a total of 11 patients enrolled in this study, 6 (54.5%) had essential blepharospasm and 5 (45.5%) had hemifacial spasm. The fellow eyes of patients with hemifacial spasm were not included, totalizing 17 eyes with spasm. Eight patients were female (72.7%) and three were male (27.3%), the male:female ratio was 1:2.6. The age ranged from 50 to 72 years old with a mean of 65.9 ± 8.2 years. The mean of high order root mean square (RMS) wavefront aberrations was 0.68 before and 0.63 one month after the treatment (p=0.01). Before the treatment, the mean of spherical aberration was 0.23 and decreased to 0.17 one month after the treatment (p=0.01). There was no significant difference in the other higher-order aberrations before and after the treatment (p>0.05). CONCLUSION: The treatment with botulium toxin may decrease spherical aberrations in patients with facial dystonia.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Blefarospasmo / Toxinas Botulínicas Tipo A / Espasmo Hemifacial / Distonia / Aberrações de Frente de Onda da Córnea / Fármacos Neuromusculares Limite: Aged / Female / Humans / Male / Middle aged Idioma: Pt Revista: Arq Bras Oftalmol Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Blefarospasmo / Toxinas Botulínicas Tipo A / Espasmo Hemifacial / Distonia / Aberrações de Frente de Onda da Córnea / Fármacos Neuromusculares Limite: Aged / Female / Humans / Male / Middle aged Idioma: Pt Revista: Arq Bras Oftalmol Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil