[Results of the treatment of growth hormone deficiency with methionine-somatotropin or recombinant somatotropin]. / Resultados del tratamiento de la deficiencia de hormona de crecimiento con metionina-somatotropina o con somatotropina-recombinante.
Bol Med Hosp Infant Mex
; 47(6): 369-71, 1990 Jun.
Article
em Es
| MEDLINE
| ID: mdl-2222818
Sixteen children with hGH deficiency were treated for a year with methionyl-somatotropin (Somatonorm) or recombinant-somatotropin (Genotropin). The hormone was administrated subcutaneously 3 time/week, 0.45-0.6 IU/kg/week. After a year of treatment, the mean growth rate in those who received Somatonorm increased from 3.96 +/- 0.8 cm/yr to 9.08 +/- 2.7 cm/yr, and in those who received Genotropin from 3.6 +/- 0.6 cm/yr to 8.58 +/- 1.1 cm/yr with no significant difference. No adverse effects were observed, but four children that received Somatonorm developed antihGH antibodies with a very low binding capacity, of less than 0.1 mg/L. All the children that received Genotropin were negative for antihGH antibodies.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hormônio do Crescimento
/
Transtornos do Crescimento
Tipo de estudo:
Etiology_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Bol Med Hosp Infant Mex
Ano de publicação:
1990
Tipo de documento:
Article
País de publicação:
México