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Physicians and patients measure different dimension on assessment for gastroesophageal reflux disease-related symptoms [corrected].
Lopez-Alvarenga, Juan Carlos; Sobrino-Cossio, Sergio; Fass, Ronnie; Vargas-Romero, Jose A.
Afiliação
  • Lopez-Alvarenga JC; Core of Biostatistics, Clinical Research Department, Hospital General de Mexico, Mexico City, Mexico. jclalvar@yahoo.com
J Neurogastroenterol Motil ; 17(4): 381-6, 2011 Oct.
Article em En | MEDLINE | ID: mdl-22148107
BACKGROUND/AIMS: Gastroesophageal reflux disease is a highly prevalent disease. Assessing treatment efficacy is critical in that clinical endpoints are properly evaluated. Clinical tools for symptoms severity assessment should be discriminative, predictive and evaluative. METHODS: In this study we compared a patient-oriented symptoms evaluation (ReQuest™) vs a structured interview assessment initiated by a physician (sickness impact profile [SIP]). Both questionnaires were analyzed in a multidimensional space using latent factors. Five dimensions were found: 1 for the short ReQuest™ questionnaire and 4 for SIP. RESULTS: We included 1,522 women and 1,296 men; mean age was 36 ± 7 years, and mean body mass index was 26 ± 4. The score questionnaire assessment evaluation by physicians and patients did not correlate between them (between r = 0.03 and 0.26) except nausea and sleep disorder (r = 0.45 and 0.51) but both were sensitive enough to detect changes after treatment (P < 0.05). Medical specialty of the physician showed effect on the score of both, ReQuest™ and SIP evaluation. Questionnaire variance decomposition due to specialist was only 2% (P < 0.05). CONCLUSIONS: While both evaluations are orthogonal (non-correlated), meaning patients and physicians measured diverse aspects of the same disease, they both were able to measure patient's improvement with treatment.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies / Qualitative_research Aspecto: Patient_preference Idioma: En Revista: J Neurogastroenterol Motil Ano de publicação: 2011 Tipo de documento: Article País de afiliação: México País de publicação:

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies / Qualitative_research Aspecto: Patient_preference Idioma: En Revista: J Neurogastroenterol Motil Ano de publicação: 2011 Tipo de documento: Article País de afiliação: México País de publicação: