Pancreatic panniculitis as the first manifestation of visceral disease--case report.
An Bras Dermatol
; 86(4 Suppl 1): S125-8, 2011.
Article
em En, Pt
| MEDLINE
| ID: mdl-22068791
Pancreatic panniculitis is a rare pathological condition affecting 2-3% of patients with pancreatic disease. In 40% of cases the condition precedes manifestations of pancreatic disease. We report the case of a 71-year-old female who presented with an erythematous tender node which had appeared one month previously, progressing to ulceration and yellowish exudation. No abdominal symptoms. Biopsy revealed fat necrosis and vacuolated macrophages represented by amorphous amphophilic areas. Laboratory examination and CT scan revealed chronic pancreatitis. It is assumed that release of pancreatic enzymes such as trypsin may enhance the permeability of the microcirculation leading to lipase and amylase causing the subcutaneous fat necrosis observed in the lesions. Histology showed "ghost cells" and, firstly, septal panniculitis, followed later by lobular panniculitis. Treatment focused on resolution of the underlying pancreatic disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Paniculite
/
Gordura Subcutânea
/
Pancreatite Crônica
Tipo de estudo:
Etiology_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
/
Pt
Revista:
An Bras Dermatol
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Espanha