Crayfish brain-protocerebrum and retina show serotonergic functional relationship.
Brain Res
; 1417: 36-44, 2011 Oct 12.
Article
em En
| MEDLINE
| ID: mdl-21911207
The results from various studies have indicated possible functional relationships between crayfish electroretinogram (ERG) rhythmic amplitude changes and the serotonergic pathways projecting from the central brain through the optic neuropils to the eye, but to date, this functional interaction has not been proven. Here, in a set of experiments using an isolated eyestalk-brain preparation, we investigated whether there is a circadian input from the brain to retina that regulates this rhythm. We sought to determine whether the protocerebral bridge (PB) stimulation affects the ERG amplitude in accordance with the zeitgeber time (ZT) and whether 5-HT modulates the associate input. Our results showed that photic stimulation of retina produced changes in both the amplitude and the frequency of spontaneous electrical activity in the protocerebral neuropils. In addition, electrical stimulation of the medial protocerebrum, particularly the PB, produced statistically significant changes in the ERG that depended on both the time of day and the level of serotonin. This suggests that pathways between retina and PB seem to be serotonergic.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Retina
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Encéfalo
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Serotonina
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Astacoidea
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Vias Neurais
Limite:
Animals
Idioma:
En
Revista:
Brain Res
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
México
País de publicação:
Holanda